Kusen' V V, Stoianovs'kyĭ S V, Babyna V P
Ukr Biokhim Zh. 1975 Jan-Feb;47(1):116-21.
There are considerable changes in the lactic and pyruvic acid contents and fructoso-1,6-diphosphatase and glucose-6-phosphatase activities in some tissues of newborn and adult guinea pigs and rabbits 24 hours after cortisone-acetate (2 mg per 100 g of body weight) injection. In the newborn animals of both species the hormone causes a decrease in the lactic and pyruvic acid concentrations and an increase in fructoso-1,6-diphosphatase activity when in the adult ones--an increase in the lactic and pyruvic acid levels and in the glucose-6-phosphatase. In the liver and kidney cortex of adult animals as compared to the newborn ones the fructoso-1,6-diphosphatase activity is significantly increased and in other tissues under study it is decreased. Certain species differences in lactic and pyruvic acid contents and in the activities of both enzymes as well as in the character of their changes under cortisone influence are found.
给新生和成年豚鼠及兔子注射醋酸可的松（每100克体重2毫克）24小时后，其某些组织中的乳酸和丙酮酸含量以及果糖-1,6-二磷酸酶和葡萄糖-6-磷酸酶活性会发生显著变化。在这两个物种的新生动物中，该激素会导致乳酸和丙酮酸浓度降低，果糖-1,6-二磷酸酶活性增加；而在成年动物中，则会使乳酸和丙酮酸水平以及葡萄糖-6-磷酸酶增加。与新生动物相比，成年动物肝脏和肾皮质中的果糖-1,6-二磷酸酶活性显著增加，而在其他研究组织中则降低。在乳酸和丙酮酸含量、两种酶的活性以及它们在可的松影响下的变化特征方面发现了某些物种差异。
