Panin L E, Nechaev Iu S, Poliakov L M
Vopr Med Khim. 1977 Mar-Apr;23(2):159-65.
Circadian rhythms of alterations in content of 11-hydroxycorticosteroids and glucose in blood as well as in the activity of phosphoenolpyruvate carboxykinase, fructose-1,6-diphosphatase and glucose-6-phosphatase in liver and kidney tissues were studied under normal and inverted luminous regimens in summer and winter seasons. These patterns were distinctly altered depending on circadian rhythms in the above-mentioned conditions. The maximal content of 11-hydroxycorticosteroids in blood did not correlate with the highest activity of the gluconeogenesis key enzymes in the periods studied. Daily alterations in the activity of phosphoemolpyruvate carboxykinase were shown to be similar to that of the fructose-1,6-diphosphatase in various tissues at different seasons. But glucose-6-phosphatase differed distinctly from these enzymes by the daily rhythm of activity. This suggests that glucose-6-phosphatase has the other mechanism for regulation of its daily rhythm.
在夏季和冬季的正常和颠倒光照方案下，研究了血液中11-羟基皮质类固醇和葡萄糖含量的昼夜节律，以及肝脏和肾脏组织中磷酸烯醇丙酮酸羧激酶、果糖-1,6-二磷酸酶和葡萄糖-6-磷酸酶的活性。在上述条件下，这些模式根据昼夜节律明显改变。在所研究的时期内，血液中11-羟基皮质类固醇的最大含量与糖异生关键酶的最高活性不相关。不同季节不同组织中磷酸烯醇丙酮酸羧激酶的活性日变化与果糖-1,6-二磷酸酶相似。但葡萄糖-6-磷酸酶的活性日节律与这些酶明显不同。这表明葡萄糖-6-磷酸酶有另一种调节其日节律的机制。
