Linden Philip A, Bueno Raphael, Mentzer Steven J, Zellos Lambros, Lebenthal Abraham, Colson Yolonda L, Sugarbaker David J, Jaklitsch Michael T
Division of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Ann Thorac Surg. 2007 Mar;83(3):1129-33. doi: 10.1016/j.athoracsur.2006.11.012.
Esophageal perforation carries a high mortality and morbidity rate, especially if treatment is delayed more than 24 hours. We present a large series of patients requiring operative treatment of esophageal perforations with attention to an infrequently used method of dealing with delayed intrathoracic perforations.
All patients undergoing operative treatment for intrathoracic esophageal perforation at the Brigham and Women's hospital between 1989 and 2003 were reviewed. Mortality, morbidity, length of stay, nature of esophageal injury, type of repair, and outcome were reviewed.
Forty-three operations for perforation of the thoracic esophagus were performed. Overall 30-day or in-hospital mortality was 7.0%, and overall morbidity was 47%. Most acute thoracic esophageal perforations were treated with primary repair and had a mortality rate of 5%, whereas most delayed perforations were treated with T-tube repair and had a mortality rate of 8.7%. The complication rate in the group repaired within 24 hours was 20%, whereas it was 61% in the group repaired after 24 hours. The complication rate in the group repaired within 72 hours was 42%, and it was 82% in the group repaired after 72 hours.
Treatment of delayed (more than 24 hours) thoracic esophageal perforations with a controlled fistula through T-tube results in a very low mortality similar to that seen with acute perforations (less than 24 hours). Morbidity and length of stay remain high. Delay in treatment of intrathoracic esophageal perforations beyond 24 and 72 hours results in a doubling of morbidity at each interval.
食管穿孔的死亡率和发病率很高,尤其是治疗延迟超过24小时的情况。我们报告了一系列需要手术治疗食管穿孔的患者,并关注一种较少使用的处理延迟性胸段穿孔的方法。
回顾了1989年至2003年在布莱根妇女医院接受胸段食管穿孔手术治疗的所有患者。对死亡率、发病率、住院时间、食管损伤的性质、修复类型和结果进行了回顾。
共进行了43例胸段食管穿孔手术。总体30天或住院死亡率为7.0%,总体发病率为47%。大多数急性胸段食管穿孔采用一期修复,死亡率为5%,而大多数延迟穿孔采用T管修复,死亡率为8.7%。24小时内修复组的并发症发生率为20%,而24小时后修复组为61%。72小时内修复组的并发症发生率为42%,72小时后修复组为82%。
通过T管形成可控瘘来治疗延迟(超过24小时)的胸段食管穿孔,其死亡率与急性穿孔(少于24小时)相似,非常低。发病率和住院时间仍然很高。胸段食管穿孔治疗延迟超过24小时和72小时,每个时间段的发病率都会加倍。