Jinks C, Jordan K, Croft P
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, UK.
Rheumatology (Oxford). 2007 May;46(5):877-81. doi: 10.1093/rheumatology/kem013. Epub 2007 Feb 17.
To determine the effect of newly developed knee pain on general health and physical function of people >or=50 yrs living in the community.
Prospective cohort study of 3907 people aged 50+ registered with three general practices in North Staffordshire, in the UK. The main outcome measures were self-reported knee pain; general health and physical function as measured by the Short Form 36 (SF-36).
Of those with no knee pain at baseline, 24% (n = 501) reported it at follow-up. There was a steep decline in physical function in this group (mean fall in SF-36 score at follow-up 10.3 points) compared with the 1558 persons who had no knee pain at baseline or follow-up (mean fall 3.3). Those with knee pain at baseline whose pain had resolved at 3-yr follow-up (n = 409) showed only minor improvements in physical functioning scores at follow-up (mean improvement -1.3).
The onset of knee pain is associated with a substantial and persistent reduction of physical function in older adults living in the community. Since knee pain is common, and reduced physical function in mid to older ages is a strong predictor of future disability and dependency, effective prevention or early treatment of knee pain at these ages is likely to have a major influence on healthy ageing in the population.
确定新出现的膝关节疼痛对社区中年龄≥50岁人群的总体健康和身体功能的影响。
对英国北斯塔福德郡三家全科诊所登记的3907名50岁及以上人群进行前瞻性队列研究。主要结局指标为自我报告的膝关节疼痛；用简短健康调查问卷（SF-36）测量的总体健康和身体功能。
在基线时无膝关节疼痛的人群中，24%（n = 501）在随访时报告出现疼痛。与在基线或随访时均无膝关节疼痛的1558人相比，该组人群的身体功能急剧下降（随访时SF-36评分平均下降10.3分）（平均下降3.3分）。基线时有膝关节疼痛且在3年随访时疼痛已缓解的人群（n = 409）在随访时身体功能评分仅略有改善（平均改善-1.3分）。
膝关节疼痛的出现与社区中老年人身体功能的显著且持续下降有关。由于膝关节疼痛很常见，且中老年人群身体功能下降是未来残疾和依赖的有力预测因素，因此在这些年龄段有效预防或早期治疗膝关节疼痛可能会对人群的健康老龄化产生重大影响。
