丝裂霉素 C 相关的射频微电灼术在动物模型鼓膜切开术中的应用。
Mitomycin C-associated radiofrequency microelectrocautery used in myringotomy in an animal model.
机构信息
Medical School, Federal University of Rio Grande do Sul.
出版信息
Braz J Otorhinolaryngol. 2009 Nov-Dec;75(6):847-51. doi: 10.1016/s1808-8694(15)30548-6.
UNLABELLED
This study aimed at describing an alternative surgical technique to the insertion of a ventilation tube in the tympanic membrane: myringotomy by radiofrequency alone and associated with mitomycin C.
AIM
to show a surgical approach that can be simple to execute, not subject to complications arising from the ventilation tube.
MATERIALS AND METHODS
we compared myringotomy by microknife and by radiofrequency microcautery (0.3 mm and 0.7 mm tips) alone and associated with mitomycin C, considering the time of tympanic closure in Wistar rats. Experimental study.
RESULTS
there was a statistically significant difference between radiofrequency myringotomy and knife myringotomy. As we analyze the radiofrequency approach with the 0.7 mm tip associated with mitomycin C (Wilcoxon test), the p value found was lower than 0.001, showing a statistical significance. The maximum tympanic membrane closure time was 44 days and the median found was 14 days.
CONCLUSION
the radiofrequency myringotomy (with the larger diameter tip) associated with mitomycin C enhances the tympanic membrane healing time.
目的
展示一种手术方法，其操作简单，且不易发生因通气管引起的并发症。
材料和方法
我们比较了单独使用射频微切开术（0.3mm 和 0.7mm 探头）和微切开术（手术刀）以及联合使用丝裂霉素 C 时的鼓膜闭合时间，研究对象为 Wistar 大鼠。这是一项实验研究。
结果
射频鼓膜切开术与手术刀鼓膜切开术之间存在统计学差异。当我们分析联合使用丝裂霉素 C 的 0.7mm 探头射频方法（Wilcoxon 检验）时，发现 p 值小于 0.001，具有统计学意义。最大鼓膜闭合时间为 44 天，中位数为 14 天。
结论
联合使用丝裂霉素 C 的较大直径探头射频鼓膜切开术可延长鼓膜愈合时间。
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