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霍达兰健康研究中睡眠时间、体重指数与代谢指标之间的关联。

The association between sleep duration, body mass index and metabolic measures in the Hordaland Health Study.

作者信息

Bjorvatn Bjørn, Sagen Ina Marie, Øyane Nicolas, Waage Siri, Fetveit Arne, Pallesen Ståle, Ursin Reidun

机构信息

Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway.

出版信息

J Sleep Res. 2007 Mar;16(1):66-76. doi: 10.1111/j.1365-2869.2007.00569.x.

Abstract

Several studies show that short self-reported sleep duration is associated with elevated body mass index (BMI). Short sleep duration may change appetite hormones, but whether this also influences metabolic measures like cholesterol and triglycerides is less clear. Furthermore, obesity is linked to increases in blood pressure, and recently, short sleep duration has been shown to be an independent risk factor for hypertension. This is a population-based cross-sectional study (The Hordaland Health Study). A subgroup of 8860 subjects, aged 40-45 years, answered a sleep questionnaire. Body weight, height and blood pressure were measured, and non-fasting blood samples were collected and analyzed for total cholesterol, HDL-cholesterol and triglycerides. Sleep duration was divided into the following subgroups: < 5, 5-5.99, 6-6.99, 7-7.99, 8-8.99 and > or = 9 h. The results show that short sleep duration was associated with elevated BMI and increased prevalence of obesity. Similar to BMI, levels of cholesterol, triglycerides, systolic and diastolic blood pressure were higher in subjects with short sleep duration. This co-variation seemed to be attributed to variables like gender, smoking and BMI. In conclusion, our study confirms a clear association between short sleep duration and elevated BMI and obesity. Furthermore, levels of total cholesterol, HDL-cholesterol, triglycerides and blood pressure were associated with sleep duration.

摘要

多项研究表明,自我报告的短睡眠时间与体重指数(BMI)升高有关。短睡眠时间可能会改变食欲激素,但这是否也会影响胆固醇和甘油三酯等代谢指标尚不清楚。此外,肥胖与血压升高有关,最近,短睡眠时间已被证明是高血压的一个独立危险因素。这是一项基于人群的横断面研究(霍达兰健康研究)。一个由8860名年龄在40 - 45岁之间的受试者组成的亚组回答了一份睡眠问卷。测量了体重、身高和血压,并采集了非空腹血样,分析了总胆固醇、高密度脂蛋白胆固醇和甘油三酯。睡眠时间分为以下亚组:<5小时、5 - 5.99小时、6 - 6.99小时、7 - 7.99小时、8 - 8.99小时以及≥9小时。结果表明,短睡眠时间与BMI升高和肥胖患病率增加有关。与BMI相似,短睡眠时间的受试者的胆固醇、甘油三酯、收缩压和舒张压水平更高。这种共变似乎归因于性别、吸烟和BMI等变量。总之,我们的研究证实了短睡眠时间与BMI升高和肥胖之间存在明显关联。此外,总胆固醇、高密度脂蛋白胆固醇、甘油三酯水平和血压与睡眠时间有关。

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