Dilley James W, Woods William J, Loeb Lisa, Nelson Kimberly, Sheon Nicolas, Mullan Joseph, Adler Barbara, Chen Sanny, McFarland Willi
AIDS Health Project, University of California-San Francisco, San Francisco, CA 94143, USA.
J Acquir Immune Defic Syndr. 2007 Apr 15;44(5):569-77. doi: 10.1097/QAI.0b013e318033ffbd.
To test the efficacy and acceptability of a single-session personalized cognitive counseling (PCC) intervention delivered by paraprofessionals during HIV voluntary counseling and testing.
HIV-negative men who have sex with men (MSM; n = 336) were randomly allocated to PCC or usual counseling (UC) between October 2002 and September 2004. The primary outcome was the number of episodes of unprotected anal intercourse (UAI) with any nonprimary partner of nonconcordant HIV serostatus in the preceding 90 days, measured at baseline, 6 months, and 12 months. Impact was assessed as "intent to treat" by random-intercept Poisson regression analysis. Acceptability was assessed by a standardized client satisfaction survey.
Men receiving PCC and UC reported comparable levels of HIV nonconcordant UAI at baseline (mean episodes: 4.2 vs. 4.8, respectively; P = 0.151). UAI decreased by more than 60% to 1.9 episodes at 6 months in the PCC arm (P < 0.001 vs. baseline) but was unchanged at 4.3 episodes for the UC arm (P = 0.069 vs. baseline). At 6 months, men receiving PCC reported significantly less risk than those receiving UC (P = 0.029 for difference to PCC). Risk reduction in the PCC arm was sustained from 6 to 12 months at 1.9 (P = 0.181), whereas risk significantly decreased in the UC arm to 2.2 during this interval (P < 0.001 vs. 6 months; P = 0.756 vs. PCC at 12 months). Significantly more PCC participants were "very satisfied" with the counseling experience (78.2%) versus UC participants (59.2%) (P = 0.002).
Both interventions were effective in reducing high-risk sexual behavior among MSM repeat testers. PCC participants demonstrated significant behavioral change more swiftly and reported a more satisfying counseling experience than UC participants.
测试在艾滋病病毒自愿咨询检测期间,由非专业人员提供的单次个性化认知咨询(PCC)干预措施的效果和可接受性。
2002年10月至2004年9月期间,将与男性发生性行为的艾滋病毒阴性男性(男男性行为者;n = 336)随机分配至PCC组或常规咨询(UC)组。主要结局指标为在基线、6个月和12个月时测量的,过去90天内与任何艾滋病毒血清学状态不一致的非主要性伴发生无保护肛交(UAI)的次数。通过随机截距泊松回归分析,以“意向性分析”评估干预效果。通过标准化的客户满意度调查评估可接受性。
接受PCC和UC的男性在基线时报告的艾滋病毒血清学状态不一致的UAI水平相当(平均次数分别为4.2次和4.8次;P = 0.151)。PCC组在6个月时UAI减少超过60%,降至1.9次(与基线相比,P < 0.001),而UC组保持在4.3次不变(与基线相比,P = 0.069)。在6个月时,接受PCC的男性报告的风险显著低于接受UC的男性(与PCC组相比差异的P = 0.029)。PCC组的风险降低在6至12个月维持在1.9次(P = 0.181),而UC组在此期间风险显著降至2.2次(与6个月相比,P < 0.001;与12个月时的PCC组相比,P = 0.756)。与UC参与者(59.2%)相比,PCC参与者对咨询体验“非常满意...”