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针对与男性发生性行为的间歇性物质使用男性的个性化认知咨询随机试验中的物质使用和饮酒结果

Substance use and drinking outcomes in Personalized Cognitive Counseling randomized trial for episodic substance-using men who have sex with men.

作者信息

Santos Glenn-Milo, Coffin Phillip O, Vittinghoff Eric, DeMicco Erin, Das Moupali, Matheson Tim, Raiford Jerris L, Carry Monique, Colfax Grant, Herbst Jeffrey H, Dilley James W

机构信息

San Francisco Department of Public Health, Substance Use Research Unit, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA.

San Francisco Department of Public Health, Substance Use Research Unit, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA.

出版信息

Drug Alcohol Depend. 2014 May 1;138:234-9. doi: 10.1016/j.drugalcdep.2014.02.015. Epub 2014 Feb 24.

Abstract

BACKGROUND

Non-dependent alcohol and substance use patterns are prevalent among men who have sex with men (MSM), yet few effective interventions to reduce their substance use are available for these men. We evaluated whether an adapted brief counseling intervention aimed at reducing HIV risk behavior was associated with secondary benefits of reducing substance use among episodic substance-using MSM (SUMSM).

METHODS

326 episodic SUMSM were randomized to brief Personalized Cognitive Counseling (PCC) intervention with rapid HIV testing or to rapid HIV testing only control. Both arms followed over 6 months. Trends in substance use were examined using GEE Poisson models with robust standard errors by arm. Reductions in frequency of use were examined using ordered logistic regression.

RESULTS

In intent-to-treat analyses, compared to men who received rapid HIV testing only, we found men randomized to PCC with rapid HIV testing were more likely to report abstaining from alcohol consumption (RR=0.93; 95% CI=0.89-0.97), marijuana use (RR=0.84; 95% CI=0.73-0.98), and erectile dysfunction drug use (EDD; RR=0.51; 95% CI=0.33-0.79) over the 6-month follow-up. PCC was also significantly associated with reductions in frequency of alcohol intoxication (OR=0.58; 95% CI=0.36-0.90) over follow-up. Furthermore, we found PCC was associated with significant reductions in number of unprotected anal intercourse events while under the influence of methamphetamine (RR=0.26; 95% CI=0.08-0.84).

CONCLUSION

The addition of adapted PCC to rapid HIV testing may have benefits in increasing abstinence from certain classes of substances previously associated with HIV risk, including alcohol and EDD; and reducing alcohol intoxication frequency and high-risk sexual behaviors concurrent with methamphetamine use.

摘要

背景

非依赖型酒精和物质使用模式在男男性行为者(MSM)中普遍存在,但针对这些男性,几乎没有有效的干预措施来减少他们的物质使用。我们评估了一种旨在降低HIV风险行为的适应性简短咨询干预是否与减少偶尔使用物质的男男性行为者(SUMSM)的物质使用的次要益处相关。

方法

326名偶尔使用物质的男男性行为者被随机分为接受快速HIV检测的简短个性化认知咨询(PCC)干预组或仅接受快速HIV检测的对照组。两组均随访6个月以上。使用具有稳健标准误差的GEE泊松模型按组检查物质使用趋势。使用有序逻辑回归检查使用频率的降低情况。

结果

在意向性分析中,与仅接受快速HIV检测的男性相比,我们发现随机接受PCC与快速HIV检测的男性在6个月随访期间更有可能报告戒酒(RR = 0.93;95%CI = 0.89 - 0.97)、不使用大麻(RR = 0.84;95%CI = 0.73 - 0.98)和不使用勃起功能障碍药物(EDD;RR = 0.51;95%CI = 0.33 - 0.79)。在随访期间,PCC还与酒精中毒频率的降低显著相关(OR = 0.58;95%CI = 0.36 - 0.90)。此外,我们发现PCC与在甲基苯丙胺影响下无保护肛交事件数量的显著减少相关(RR = 0.26;95%CI = 0.08 - 0.84)。

结论

在快速HIV检测中加入适应性PCC可能有助于提高对某些以前与HIV风险相关的物质的戒断率,包括酒精和EDD;并降低酒精中毒频率以及与甲基苯丙胺使用同时发生的高危性行为。

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