Roscoe Andrew, Kanellakos George W, McRae Karen, Slinger Peter
Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, Ontario.
Anesth Analg. 2007 Mar;104(3):655-8. doi: 10.1213/01.ane.0000255171.94527.c7.
High endotracheal cuff pressures have been shown to cause high mucosal pressures and a reduction in mucosal blood flow, with the risk of mucosal ischemia. We aimed to directly measure the pressure exerted by the bronchial cuffs of double-lumen tubes (DLT) and by the cuffs of three new designs of endobronchial blocker (EBB).
Using a validated in vitro model and a previously described technique, we measured the static pressures exerted by the cuff of DLTs and EBBs with 1 mL increments in cuff volume until maximum inflation was achieved. The study was repeated under dynamic conditions of simulated positive pressure ventilation.
The pressures exerted by the cuffs of DLTs ranged from 16-155 mm Hg. Pressures exerted by the EBB cuffs ranged from 39-194 mm Hg. At intra-cuff volumes required to create a seal to 25 cm H2O positive pressure, the pressures exerted by the cuffs of all the devices were <30 mm Hg.
A transmitted pressure <30 mm Hg has been recommended to avoid mucosal injury. Our study shows that at clinically relevant cuff volumes, the pressures exerted by the cuffs do not exceed the recommended safe limit.
已证实高气管内套囊压力会导致高黏膜压力并减少黏膜血流,存在黏膜缺血风险。我们旨在直接测量双腔管(DLT)支气管套囊以及三种新型支气管阻塞器(EBB)套囊所施加的压力。
使用经过验证的体外模型和先前描述的技术,我们以1 mL的套囊容积增量测量DLT和EBB套囊所施加的静态压力,直至达到最大充气量。在模拟正压通气的动态条件下重复该研究。
DLT套囊所施加的压力范围为16 - 155 mmHg。EBB套囊所施加的压力范围为39 - 194 mmHg。在为达到25 cm H₂O正压密封所需的套内容积时,所有装置套囊所施加的压力均<30 mmHg。
已建议传递压力<30 mmHg以避免黏膜损伤。我们的研究表明,在临床相关的套囊容积下,套囊所施加的压力不超过推荐的安全限度。