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食管自发性破裂(博赫哈夫综合征)的管理:18例单中心经验

Management of spontaneous rupture of the oesophagus (Boerhaave's syndrome): single centre experience of 18 cases.

作者信息

Prichard R, Butt J, Al-Sariff N, Frohlich S, Murphy S, Manning B, Ravi N, Reynolds J V

机构信息

Dept of Clinical Surgery, St James's Hospital and Trinity College Dublin.

出版信息

Ir J Med Sci. 2006 Oct-Dec;175(4):66-70. doi: 10.1007/BF03167971.

Abstract

BACKGROUND

Spontaneous oesophageal rupture (Boerhaave's syndrome) is rare, and carries a high attendant risk of mortality.

METHODS

A retrospective eight-year review from a tertiary unit.

RESULTS

Eighteen patients were managed, with a mean age of 57 (39 - 88 years). Eight patients presented early and underwent surgery, seven with primary closure and one with exclusion and diversion. There was one death in this group. Ten patients were managed conservatively. In this group, two underwent an oesophagectomy because of failed conservative measures, and four had an endoprosthesis inserted. One patient died in this group on the first admission, but two patients with stents in situ died from massive bleeding relating to an aorto-oesophageal fistula at 39 days and 189 days respectively following presentation.

CONCLUSIONS

Surgical intervention remains the gold standard when the diagnosis is made early. For late diagnoses, this series suggests caution in the use of endoprostheses.

摘要

背景

自发性食管破裂(Boerhaave综合征)较为罕见,且伴随的死亡风险很高。

方法

对一家三级医疗机构进行为期八年的回顾性研究。

结果

共治疗18例患者,平均年龄57岁(39 - 88岁)。8例患者早期就诊并接受手术,其中7例行一期缝合,1例行旷置及转流术。该组有1例死亡。10例患者接受保守治疗。在这组患者中,2例因保守治疗失败而行食管切除术,4例置入了内支架。该组有1例患者在首次入院时死亡,但2例置入支架的患者分别在就诊后39天和189天死于与主动脉食管瘘相关的大出血。

结论

早期诊断时,手术干预仍是金标准。对于晚期诊断,本系列研究提示在使用内支架时应谨慎。

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