Al Shukairy Haneen, Alamoudi Najlaa, Farsi Najat, Al Mushayt Abdullah, Masoud Ibrahim
Department of Preventive Dental Sciences, Faculty of Dentistry, King Abdulaziz University, Saudi Arabia.
J Clin Pediatr Dent. 2006 Winter;31(2):80-5. doi: 10.17796/jcpd.31.2.w8555245202l6761.
Early childhood caries (ECC) is recognized as an infectious disease. The first step in its development is primary infection by the bacterium S. mutans which has been identified as the primary etiologic factors in dental caries. Lactobacilli were also found to play a role in the progression of the disease. However, the underlying mechanism of immune response to caries is still unclear. The purpose of this study was to assess the level of cariogenic bacteria namely S. mutans and lactobacilli in caries free children, and children with SECC and their corresponding mothers. he study also aims at correlating the children's levels to their mothers. Sixty children and their mothers attending the dental clinic in King Abdulaziz University participated in our study. Their age ranged from 3 - 5 years. The study groups consisted of 30 children with SECC and a control group comprising of 30 caries free children. Children together with their mothers were examined and their caries level was recorded. Stimulated saliva was collected from each participant for bacterial, immunological assessment, and Lactobacilli counts in each sample were determined Children with SECC had higher levels of S. mutans and Lactobacilli than caries free children. The mothers of children with SECC had a statistically higher count of Lactobacilli than caries free children's mothers. However, the difference was not statistically significant with respect to their S. mutans counts. A significant relationship exists among the mother-child pair in the SECC group with respect to S. mutans level in saliva.
幼儿龋齿（ECC）被认为是一种传染病。其发展的第一步是由变形链球菌引发的原发性感染，该细菌已被确定为龋齿的主要病因。乳酸杆菌也被发现与疾病的进展有关。然而，对龋齿免疫反应的潜在机制仍不清楚。本研究的目的是评估无龋儿童、重度早期儿童龋（SECC）儿童及其相应母亲口腔中致龋菌即变形链球菌和乳酸杆菌的水平。该研究还旨在将儿童的水平与他们母亲的水平进行关联。60名儿童及其母亲在阿卜杜勒阿齐兹国王大学牙科诊所就诊并参与了我们的研究。他们的年龄在3至5岁之间。研究组由30名患有SECC的儿童组成，对照组由30名无龋儿童组成。对儿童及其母亲进行检查并记录他们的龋齿情况。从每位参与者收集刺激唾液用于细菌学、免疫学评估，并测定每个样本中的乳酸杆菌计数。患有SECC的儿童比无龋儿童的变形链球菌和乳酸杆菌水平更高。患有SECC的儿童的母亲的乳酸杆菌计数在统计学上高于无龋儿童的母亲。然而，就变形链球菌计数而言，差异无统计学意义。在SECC组中，母婴对之间唾液中变形链球菌水平存在显著关系。
