原发性心脏浆母细胞性（弥漫性大B细胞）淋巴瘤酷似伴有壁血栓的左心室动脉瘤。
Primary cardiac plasmablastic (diffuse large B-cell) lymphoma mimicking left ventricular aneurysm with mural thrombus.
作者信息
Miller Dylan V, Mookadam Farouk, Mookadam Martina, Edwards William D, Macon William R
机构信息
Division of Anatomic Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
出版信息
Cardiovasc Pathol. 2007 Mar-Apr;16(2):111-4. doi: 10.1016/j.carpath.2006.09.003.
Primary cardiac lymphoma is rare and is usually of the non-Hodgkin type. By definition, it involves only the heart and the pericardium, with no evidence of extracardiac disease. Primary cardiac lymphoma accounts for 1% of primary cardiac tumors and 0.5% of extranodal lymphomas [Gowda RM, Kahn RA. Clinical perspectives of primary cardiac lymphoma. Angiology 2003;54(5):599-604]. On the other hand, secondary cardiac involvement can occur in approximately 20% of patients with disseminated extracardiac lymphoma [Gowda RM, Kahn RA. Clinical perspectives of primary cardiac lymphoma. Angiology 2003;54(5):599-604]. The majority of primary cardiac lymphomas are diffuse large B-cell lymphomas with centroblastic or immunoblastic cytologic features. Herein, we describe an exceptional case of a primary cardiac plasmablastic variant of diffuse large B-cell lymphoma (Epstein-Barr virus-positive) presenting in an immunocompetent host with chest pain that mimicked a left ventricular apical thrombus.
原发性心脏淋巴瘤较为罕见，通常为非霍奇金型。根据定义，它仅累及心脏和心包，无心脏外疾病的证据。原发性心脏淋巴瘤占原发性心脏肿瘤的1%，占结外淋巴瘤的0.5%[Gowda RM，Kahn RA。原发性心脏淋巴瘤的临床观点。血管学2003；54(5)：599 - 604]。另一方面，约20%的播散性心脏外淋巴瘤患者会出现继发性心脏受累[Gowda RM，Kahn RA。原发性心脏淋巴瘤的临床观点。血管学2003；54(5)：599 - 604]。大多数原发性心脏淋巴瘤是具有中心母细胞或免疫母细胞细胞学特征的弥漫性大B细胞淋巴瘤。在此，我们描述一例罕见病例，一名免疫功能正常的宿主出现胸痛，表现为弥漫性大B细胞淋巴瘤（爱泼斯坦 - 巴尔病毒阳性）的原发性心脏浆母细胞变异型，酷似左心室心尖部血栓。
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