Fealey Michael E, Edwards William D, Reynolds Carol A, Pellikka Patricia A, Dearani Joseph A
Mayo Summer Laboratory Assistant Program, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Cardiovasc Pathol. 2007 Mar-Apr;16(2):115-8. doi: 10.1016/j.carpath.2006.09.002.
Cardiac calcified amorphous tumors (CATs) represent degenerating intracavitary mural thrombi that can mimic neoplasms and cause symptoms due to embolization or obstruction. Surgical excision is generally curative. Postoperative recurrences have not been previously reported.
Medical, surgical, and pathological records were reviewed in a patient who had undergone removal of a recurrent cardiac CAT.
The patient, now a 23-year-old woman, had undergone excision of the initial right ventricular mass on November 4, 2003, because of recent pulmonary embolization. Extensive clinical evaluation showed no coagulation abnormality. Follow-up postoperative echocardiograms showed incomplete excision and subsequent enlargement. As a result, the recurrent mass was excised on March 14, 2006. Microscopic evaluation showed degenerating and focally calcifying thrombus, without neoplastic features.
Cardiac CAT may recur and enlarge following surgical excision. Periodic postoperative follow-up with cardiac imaging studies may be indicated, particularly if there is evidence of incomplete excision.
心脏钙化性无定形肿瘤(CATs)是退化的腔内壁血栓,可酷似肿瘤,并因栓塞或阻塞而导致症状。手术切除通常可治愈。此前尚未有术后复发的报道。
对一名接受复发性心脏CAT切除手术患者的医学、手术及病理记录进行回顾。
该患者现为一名23岁女性,因近期发生肺栓塞,于2003年11月4日接受了初始右心室肿块切除术。全面的临床评估显示无凝血异常。术后随访超声心动图显示切除不完全且肿块随后增大。因此,于2006年3月14日切除了复发性肿块。显微镜评估显示为退化且局灶性钙化的血栓,无肿瘤特征。
心脏CAT在手术切除后可能复发并增大。术后可能需要定期进行心脏影像学检查随访,尤其是在有切除不完全证据的情况下。