Yamana Fumio, Domae Keitaro, Shirakawa Yukitoshi, Masai Takafumi
Department of Cardiovascular Surgery, Osaka Police Hospital, Kitayama-cho 10-31, Tennouji-ku, Osaka 543-0035, Japan.
J Cardiol Cases. 2022 Jan 3;25(5):297-299. doi: 10.1016/j.jccase.2021.11.010. eCollection 2022 May.
Cardiac calcified amorphous tumors are rare non-neoplastic intracavitary masses. Herein, we report a case of a 75-year-old woman who presented with dyspnea on exertion and multiple cerebral infarctions 3 months prior. Transthoracic echocardiography showed severe mitral regurgitation from the posterior mitral leaflet with valve perforation and severe mitral annular calcification. In addition, we observed a 13 mm mobile high echogenic mass, suggesting healed infective endocarditis. The mass was successfully resected, and the mitral valve was replaced with a bovine pericardial patch for the decalcified annulus. Histopathological examination confirmed cardiac calcified amorphous tumor; the postoperative course was uneventful. Mitral valve replacement and annulus patch repair effectively prevented postoperative recurrent systemic embolization. < Calcified amorphous tumor (CAT) is a risk factor for systemic embolism. Cardiac CAT destroying the mitral valve tissue and causing mitral valvular disease have been scarcely reported. We present a case of cardiac CAT with mitral valve perforation and suspected systemic embolization, treated successfully through mitral valve replacement and calcified lesion coverage by surgical resection and patch repair.>.
心脏钙化性无定形肿瘤是罕见的非肿瘤性心腔内肿块。在此，我们报告一例75岁女性患者，该患者3个月前出现劳力性呼吸困难和多发性脑梗死。经胸超声心动图显示二尖瓣后叶严重二尖瓣反流伴瓣膜穿孔和严重二尖瓣环钙化。此外，我们观察到一个13毫米的活动高回声团块，提示感染性心内膜炎已愈合。该团块被成功切除，二尖瓣用牛心包补片置换以修复钙化的瓣环。组织病理学检查确诊为心脏钙化性无定形肿瘤；术后过程顺利。二尖瓣置换和瓣环补片修复有效预防了术后复发性全身栓塞。<钙化性无定形肿瘤（CAT）是全身栓塞的危险因素。心脏CAT破坏二尖瓣组织并导致二尖瓣疾病的情况鲜有报道。我们报告一例伴有二尖瓣穿孔和疑似全身栓塞的心脏CAT病例，通过二尖瓣置换以及手术切除和补片修复覆盖钙化病变成功治疗。>
