Braun Ralph Peter, Baran Robert, Le Gal Frederique Anne, Dalle Stephane, Ronger Sandra, Pandolfi Roberta, Gaide Olivier, French Lars Einar, Laugier Paul, Saurat Jean Hilaire, Marghoob Ashfaq Ahmed, Thomas Luc
Pigmented Skin Lesion Unit, Department of Dermatology, University Hospital Geneva, Switzerland.
J Am Acad Dermatol. 2007 May;56(5):835-47. doi: 10.1016/j.jaad.2006.12.021. Epub 2007 Feb 22.
Longitudinal pigmentation of the nail is very common. The differential diagnosis varies from subungual hematoma, to a fungal infection, to a melanocytic lesion (lentigo, nevus melanoma, etc.) to others. Often, dermatologists do not feel at ease with these pathologies and management is often not clear. In many cases, a biopsy is not helpful because an inadequate technique was chosen. The use of noninvasive techniques such as dermoscopy has been described to be useful for the preoperative evaluation and the management decision. Using these technique, one will be able to reduce the number of unnecessary surgeries and to choose the most adequate biopsy technique. In this article, we will review the management, including diagnosis as well as differential diagnosis of nail pigmentations and propose a new algorithm for the non invasive diagnosis of nail pigmentation.
指甲纵向色素沉着非常常见。鉴别诊断范围从甲下血肿、真菌感染、黑素细胞病变(雀斑样痣、痣、黑色素瘤等)到其他情况。通常,皮肤科医生对这些病症并不放心,治疗方案往往也不明确。在许多情况下,活检并无帮助,因为选择的技术不恰当。已有人描述使用皮肤镜等非侵入性技术对术前评估和治疗决策有用。使用这些技术,能够减少不必要的手术数量,并选择最恰当的活检技术。在本文中,我们将回顾指甲色素沉着的治疗,包括诊断和鉴别诊断,并提出一种新的指甲色素沉着非侵入性诊断算法。