Brinson George M, Chen Douglas A, Arriaga Moisés A
Wilmington ENT, Wilmington, NC, USA.
Otolaryngol Head Neck Surg. 2007 Mar;136(3):415-21. doi: 10.1016/j.otohns.2006.08.031.
This study compares the efficacy of endolymphatic mastoid shunt (EMS) versus endolymphatic sac decompression (ESD) without sac incision for the treatment of Ménière's disease.
The AAO-HNS Guidelines for the Diagnosis and Evaluation of Therapy in Ménière's disease were used to retrospectively identify suitable candidates for the study. All patients who failed medical management and underwent either endolymphatic-mastoid shunt (EMS) (n = 88) or endolymphatic sac decompression (ESD) (n = 108) were selected for review using the AAO-HNS guidelines. The study was carried out at a tertiary care neurotology private practice.
EMS and ESD were equally effective in reducing the incidence and severity of vertigo attacks with significant improvement in 67 percent and 66 percent of patients, respectively.
Both EMS and ESD are effective, nondestructive alternatives for patients who have failed medical management of Ménière's disease with similar long-term hearing outcomes.
This is the only study within the same institution using AAO-HNS guidelines comparing EMS versus ESD.
本研究比较内淋巴囊乳突分流术（EMS）与不切开囊的内淋巴囊减压术（ESD）治疗梅尼埃病的疗效。
采用美国耳鼻咽喉头颈外科学会（AAO-HNS）梅尼埃病诊断与治疗评估指南，回顾性确定本研究的合适人选。所有药物治疗无效且接受内淋巴囊乳突分流术（EMS）（n = 88）或内淋巴囊减压术（ESD）（n = 108）的患者，均按照AAO-HNS指南进行回顾性分析。本研究在一家三级医疗神经耳科学私人诊所开展。
EMS和ESD在降低眩晕发作的发生率和严重程度方面同样有效，分别有67%和66%的患者有显著改善。
对于梅尼埃病药物治疗无效的患者，EMS和ESD都是有效的、非破坏性的治疗选择，且长期听力结果相似。
这是同一机构内唯一一项采用AAO-HNS指南比较EMS与ESD的研究。
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