Abengoechea-Hernández S, Elizalde-Montagut J, Fideliz de la Paz-Dalisay M
Departamento de Vítreo-Retina, Centro de Oftalmología Barraquer, Barcelona, España.
Arch Soc Esp Oftalmol. 2007 Feb;82(2):117-20. doi: 10.4321/s0365-66912007000200011.
We present the case of a patient who underwent photodynamic therapy (PDT) for adult-onset foveomacular vitelliform dystrophy (AFVD) at another clinic, having been misdiagnosed as having a choroidal neovascular membrane. Two years post-treatment, the patient had severe central visual loss and showed angiographic signs of choroidal hypoperfusion.
AFVD is a rare clinical entity, usually having a fair visual prognosis, although some cases may show episodes of severe visual loss during their clinical course. Optical coherence tomography (OCT) is valuable in revealing the distinct images of AFVD from the features of a choroidal neovascular membrane. PDT using verteporfin may have negative long term effects if used in patients with AFVD.
我们介绍了一名患者的病例，该患者在另一家诊所接受了光动力疗法（PDT）治疗成人迟发性黄斑中心凹卵黄样营养不良（AFVD），此前被误诊为脉络膜新生血管膜。治疗两年后，患者出现严重的中心视力丧失，并显示出脉络膜灌注不足的血管造影迹象。
AFVD是一种罕见的临床病症，通常视力预后良好，尽管有些病例在其临床过程中可能会出现严重视力丧失的发作。光学相干断层扫描（OCT）对于从脉络膜新生血管膜的特征中揭示AFVD的独特图像很有价值。如果用于AFVD患者，使用维替泊芬的光动力疗法可能会有负面的长期影响。
