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教育水平与恶性黑色素瘤风险

Level of education and the risk of malignant melanoma.

作者信息

Lee P Y, Silverman M K, Rigel D S, Vossaert K A, Kopf A W, Bart R S, Garfinkel L, Levenstein M J

机构信息

Department of Dermatology, New York University (NYU) School of Medicine, New York.

出版信息

J Am Acad Dermatol. 1992 Jan;26(1):59-63. doi: 10.1016/0190-9622(92)70007-3.

Abstract

BACKGROUND

The risk for the development of malignant melanoma has been reported to be higher in persons with more formal education than in individuals with less.

OBJECTIVE

To study whether those with more formal education are indeed at more risk for malignant melanoma than those with less formal education.

METHODS

This case-control study explores the relation between education and melanoma risk by analyzing data collected by the American Cancer Society. A total of 1.2 million people were surveyed for a history of cancer and followed up for 6 years for the development of any cancer. In total, 2780 white persons had a history of malignant melanoma or developed malignant melanoma during the study period. The controls were age-, sex-, and geographically matched white persons selected from the remaining people enrolled.

RESULTS

Both men and women were shown to have a statistically significant increase in the relative risk for malignant melanoma with increasing education level (p less than 0.001 and p = 0.001, respectively). This relation was more striking in men when the relative risk with 95% confidence interval was calculated by sex for each education level.

CONCLUSION

Americans with more formal education are at greater risk for malignant melanoma than those with less education.

摘要

背景

据报道,接受正规教育程度较高的人患恶性黑色素瘤的风险高于受教育程度较低的人。

目的

研究接受正规教育程度较高的人是否确实比受正规教育程度较低的人患恶性黑色素瘤的风险更高。

方法

这项病例对照研究通过分析美国癌症协会收集的数据,探讨教育与黑色素瘤风险之间的关系。总共对120万人进行了癌症病史调查,并对其进行了6年的随访,以观察是否发生任何癌症。在研究期间,共有2780名白人有恶性黑色素瘤病史或患上了恶性黑色素瘤。对照组是从其余登记入组的人中挑选出的年龄、性别和地理位置相匹配的白人。

结果

随着教育水平的提高,男性和女性患恶性黑色素瘤的相对风险均有统计学意义的显著增加(分别为p<0.001和p = 0.001)。当按性别计算每个教育水平的95%置信区间的相对风险时,这种关系在男性中更为明显。

结论

接受正规教育程度较高的美国人患恶性黑色素瘤的风险高于受教育程度较低的人。

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