Araujo Leila Fernandes, de Matos Soeiro Alexandre, Fernandes Juliano Lara, Pesaro Antônio Eduardo, Serrano Carlos V
Heart Institute (InCor), University of São Paulo, School of Medicine, Brazil.
Vasc Health Risk Manag. 2006;2(4):465-75. doi: 10.2147/vhrm.2006.2.4.465.
Despite numerous studies on women's cardiac health throughout the past decade, the number of female deaths caused by cardiovascular disease still rises and remains the leading cause of death in women in most areas of the world. Novel studies have demonstrated that cardiovascular disease, and more specifically coronary artery disease presentations in women, are different than those in men. In addition, pathology and pathophysiology of the disease present significant gender differences, which leads to difficulties concerning diagnosis, treatment and outcome of the female population. The reason for this disparity is all steps for female cardiovascular disease evaluation, treatment and prevention are not well elucidated; and an area for future research. This review brings together the most recent studies published in the field of coronary artery disease in women and points out new directions for future investigation on some of the important issues.
尽管在过去十年间针对女性心脏健康进行了大量研究，但心血管疾病导致的女性死亡人数仍在上升，并且在世界大部分地区仍是女性的主要死因。新的研究表明，心血管疾病，尤其是女性的冠状动脉疾病表现与男性不同。此外，该疾病的病理学和病理生理学存在显著的性别差异，这给女性人群的诊断、治疗和预后带来了困难。这种差异的原因在于女性心血管疾病评估、治疗和预防的所有环节都尚未得到充分阐明，这也是未来研究的一个领域。本综述汇集了女性冠状动脉疾病领域发表的最新研究，并指出了未来针对一些重要问题进行调查的新方向。
