Matinzadeh Zahra Khalili, Beiragdar Fatemeh, Kavemanesh Zohreh, Abolgasemi Hasan, Amirsalari Susan
Department of Paediatrics, Bagyatallah Medical Sciences University, Tehran, Iran.
Trop Doct. 2007 Jan;37(1):47-9. doi: 10.1258/004947507779951880.
Ophthalmia neonatorum is a form of conjunctivitis occurring in infants younger than 4 weeks. It can be a leading cause of blindness in newborns. In this random clinical case-control study, ophthalmia neonatorum was investigated in one university centre. In this study, prophylactic effect of normal saline and ophthalmic erythromycin was compared with a group not receiving any prophylaxis. The first group received ophthalmic erythromycin ointment (0.5%), the second group were distilled one drop of normal saline into each eye, and the third group did not take any prophylaxis. Within the first 10 days of life, conjunctivitis developed in 138 newborns (13.8%). Of conjunctivitis cases, 29.7% were in erythromycin group, 31.9% in normal saline group and 38.4% were in no-prophylaxis group. In general, no significant difference was observed among the three groups (P > 0.05).
新生儿眼炎是一种发生在4周龄以下婴儿的结膜炎。它可能是新生儿失明的主要原因。在这项随机临床病例对照研究中，在一个大学中心对新生儿眼炎进行了调查。在本研究中，将生理盐水和眼科用红霉素的预防效果与未接受任何预防措施的一组进行了比较。第一组接受眼科用红霉素眼膏（0.5%），第二组每只眼睛滴入一滴蒸馏水，第三组不采取任何预防措施。在出生后的前10天内，138名新生儿（13.8%）发生了结膜炎。在结膜炎病例中，红霉素组占29.7%，生理盐水组占31.9%，无预防措施组占38.4%。总体而言，三组之间未观察到显著差异（P>0.05）。
