Kelleher Michael O, Murray Dylan J, McGillivary Anne, Kamel Mahmoud H, Allcutt David, Earley Michael J
Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
J Neurosurg. 2006 Nov;105(5 Suppl):382-4. doi: 10.3171/ped.2006.105.5.382.
The neurobehavioral morbidity of nonsyndromic trigonocephaly is incompletely understood. The purpose of this study was twofold: first, to assess the degree of developmental, educational, and behavioral problems in patients with nonsyndromic trigonocephaly and second, to establish whether patients with mild degrees of trigonocephaly had a lower frequency of such problems.
The authors performed an observational study of the frequency of developmental, educational, and behavioral problems in 63 children with trigonocephaly at the National Craniofacial Centre in the Republic of Ireland between 1989 and 2004. The parents of the children completed a follow-up questionnaire. Thirty percent of patients had a mild form of trigonocephaly and were treated conservatively. The remainder underwent surgical correction. Speech and/or language delay was reported in 34% of the children. Thirty-three percent of the children needed to be assessed by a school psychologist, and 47% were receiving remedial or resource hours within the school system. Twenty percent of children required a special needs classroom assistant because of behavioral issues, and 37% of parents expressed concerns about their child's behavior. There were no statistically significant differences between children treated with surgery and those who had a mild deformity and were treated conservatively.
Nonsyndromic trigonocephaly is associated with a high frequency of developmental, educational, and behavioral problems. The frequency of these problems is not related to the severity of the trigonocephaly.
非综合征性三角头畸形的神经行为发病率尚未完全明确。本研究有两个目的：其一，评估非综合征性三角头畸形患者的发育、教育和行为问题程度；其二，确定轻度三角头畸形患者此类问题的发生率是否较低。
作者对1989年至2004年间爱尔兰共和国国家颅面中心的63例三角头畸形儿童的发育、教育和行为问题发生率进行了一项观察性研究。这些儿童的家长完成了一份随访问卷。30%的患者为轻度三角头畸形，接受保守治疗。其余患者接受手术矫正。34%的儿童报告有言语和/或语言发育迟缓。33%的儿童需要学校心理学家进行评估，47%的儿童在学校系统内接受辅导或资源课程。20%的儿童因行为问题需要特殊需求课堂助理，37%的家长对其孩子的行为表示担忧。手术治疗的儿童与轻度畸形且接受保守治疗的儿童之间在统计学上无显著差异。
非综合征性三角头畸形与发育、教育和行为问题的高发生率相关。这些问题的发生率与三角头畸形的严重程度无关。
