腺嘌呤核苷酸和鸟嘌呤核苷酸对分离的鸡肝细胞和肾细胞从头合成尿酸的影响。
The effects of adenine nucleotides and guanine nucleotides on urate synthesis de novo by isolated chick liver and kidney cells.
作者信息
Badenoch-Jones P, Buttery P J
出版信息
Biochem J. 1975 Jun;148(3):599-601. doi: 10.1042/bj1480599.
Abstract
Isolated chick liver and kidney cells produce urate de novo from glycine, and this is partially inhibited by 1 mm-AMP and by 1 mm-GMP in liver cells but not in kidney cells. Azaserine fully inhibits this synthesis de novo, but attempts to isolate formylglycine amide ribonucleotide from azaserine-blocked cells were unsuccessful.
摘要
分离的鸡肝细胞和肾细胞能从甘氨酸从头合成尿酸盐，在肝细胞中，1毫摩尔/升的AMP和1毫摩尔/升的GMP可部分抑制这一过程，但在肾细胞中则无此现象。重氮丝氨酸可完全抑制这种从头合成，但从经重氮丝氨酸处理的细胞中分离甲酰甘氨酸酰胺核糖核苷酸的尝试未获成功。
相似文献
1
The effects of adenine nucleotides and guanine nucleotides on urate synthesis de novo by isolated chick liver and kidney cells.腺嘌呤核苷酸和鸟嘌呤核苷酸对分离的鸡肝细胞和肾细胞从头合成尿酸的影响。
Biochem J. 1975 Jun;148(3):599-601. doi: 10.1042/bj1480599.
2
The effects of added purines on urate and purine synthesis de novo by isolated chick liver, kidney and lymphoid cells.添加的嘌呤对分离的鸡肝脏、肾脏和淋巴细胞从头合成尿酸盐和嘌呤的影响。
Biochem J. 1976 Sep 15;158(3):549-56. doi: 10.1042/bj1580549.
3
Purine metabolism and urate biosynthesis in isolated chicken hepatocytes.分离的鸡肝细胞中的嘌呤代谢与尿酸盐生物合成
Arch Biochem Biophys. 1984 Sep;233(2):507-14. doi: 10.1016/0003-9861(84)90474-0.
4
The effects of adenine derivatives on urate biosynthesis by isolated chicken liver cells [proceedings].腺嘌呤衍生物对离体鸡肝细胞尿酸生物合成的影响[会议论文集]
Biochem Soc Trans. 1980 Feb;8(1):140-1. doi: 10.1042/bst0080140.
5
Urate synthesis in the perfused chick liver.灌注鸡肝中的尿酸合成。
Biochem J. 1974 Nov;144(2):189-98. doi: 10.1042/bj1440189.
6
7
[Pathways of inosine monophosphate transformation in the chicken liver].[鸡肝脏中肌苷单磷酸的转化途径]
Biokhimiia. 1988 Feb;53(2):182-7.
8
The enzymic phosphorylation of N6-(delta 2-isopentenyl) adenosine in chick liver homogenates.
Can J Biochem. 1973 Oct;51(10):1341-6. doi: 10.1139/o73-177.
9
Influence of allopurinol and azaserine on nitrogen metabolism in the chick.别嘌醇和重氮丝氨酸对雏鸡氮代谢的影响。
Poult Sci. 1972 May;51(3):882-90. doi: 10.3382/ps.0510882.
10
Intense exercise induces the degradation of adenine nucleotide and purine nucleotide synthesis via de novo pathway in the rat liver.剧烈运动通过从头合成途径诱导大鼠肝脏中腺嘌呤核苷酸降解和嘌呤核苷酸合成。
Eur J Appl Physiol. 2006 Mar;96(5):543-50. doi: 10.1007/s00421-005-0106-4. Epub 2005 Dec 21.
引用本文的文献
1
A Review of Emerging Goose Astrovirus Causing Gout.新兴鹅星状病毒引起痛风的研究综述。
Biomed Res Int. 2022 Aug 28;2022:1635373. doi: 10.1155/2022/1635373. eCollection 2022.
2
The effects of added purines on urate and purine synthesis de novo by isolated chick liver, kidney and lymphoid cells.添加的嘌呤对分离的鸡肝脏、肾脏和淋巴细胞从头合成尿酸盐和嘌呤的影响。
Biochem J. 1976 Sep 15;158(3):549-56. doi: 10.1042/bj1580549.
本文引用的文献
1
The synthesis of uric acid in the avian organism: hypoxanthine as an intermediary metabolite.鸟类机体中尿酸的合成：次黄嘌呤作为中间代谢产物。
Biochem J. 1936 Aug;30(8):1380-5. doi: 10.1042/bj0301380.
2
3
Feedback inhibition of purine biosynthesis in ascites tumor cells.腹水肿瘤细胞中嘌呤生物合成的反馈抑制
J Biol Chem. 1962 Aug;237:2631-5.
4
Purinethiols as feedback inhibitors of purine synthesis in ascites tumor cells.嘌呤硫醇作为腹水肿瘤细胞中嘌呤合成的反馈抑制剂。
Cancer Res. 1961 Jun;21:642-9.
5
6
In vivo sensitivity of normal and neoplastic mouse tissues to azaserine.
Cancer Res. 1957 Sep;17(8):804-8.
7
On the occurrence of glycinamide ribotide and its formyl derivative.关于甘氨酰胺核苷酸及其甲酰衍生物的出现。
J Biol Chem. 1956 Aug;221(2):555-67.
8
Studies on uric acid and related compounds. I. Quantitative determination of uric acid in biological fluids.尿酸及相关化合物的研究。I. 生物体液中尿酸的定量测定。
J Biol Chem. 1954 Nov;211(1):149-53.
9
Phylogenic aspects of different regulatory mechanisms of glutamine metabolism.谷氨酰胺代谢不同调节机制的系统发生学方面。
Adv Enzyme Regul. 1970;8:73-81. doi: 10.1016/0065-2571(70)90009-9.
10
Effect of riboflavin deficiency on the metabolism of oxypurines in chicks.核黄素缺乏对雏鸡氧嘌呤代谢的影响。
Can J Physiol Pharmacol. 1971 Dec;49(12):1059-62. doi: 10.1139/y71-150.
Zotero 插件