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车前草作为治疗剂和药物递送剂。

Psyllium as therapeutic and drug delivery agent.

作者信息

Singh Baljit

机构信息

Department of Chemistry, Himachal Pradesh University, Shimla 171005, India.

出版信息

Int J Pharm. 2007 Apr 4;334(1-2):1-14. doi: 10.1016/j.ijpharm.2007.01.028. Epub 2007 Jan 21.

DOI:10.1016/j.ijpharm.2007.01.028
PMID:17329047
Abstract

There is no doubt that fibers, in particular viscous dietary fibers, have positive effects on human health, both in the prevention and in treatment of chronic diseases. Dietary fibers from psyllium have been used extensively both as pharmacological supplements, food ingredients, in processed food to aid weight control, to regulation of glucose control for diabetic patients and reducing serum lipid levels in hyperlipidemics. Keeping in view, the pharmacological importance of psyllium polysaccharide and its gel-forming nature, this article discusses the therapeutic value of psyllium for the treatment of constipation, diarrhea, irritable bowel syndrome, inflammatory bowel disease-ulcerative colitis, colon cancer, diabetes and hypercholesterolemia and exploitation of psyllium for developing drug delivery systems.

摘要

毫无疑问,纤维,尤其是粘性膳食纤维,对人类健康具有积极影响,无论是在预防还是治疗慢性病方面。来自车前草的膳食纤维已被广泛用作药物补充剂、食品成分,用于加工食品中以帮助控制体重、调节糖尿病患者的血糖以及降低高脂血症患者的血脂水平。鉴于车前草多糖的药理重要性及其形成凝胶的性质,本文讨论了车前草在治疗便秘、腹泻、肠易激综合征、炎症性肠病——溃疡性结肠炎、结肠癌、糖尿病和高胆固醇血症方面的治疗价值,以及利用车前草开发药物递送系统。

相似文献

1
Psyllium as therapeutic and drug delivery agent.车前草作为治疗剂和药物递送剂。
Int J Pharm. 2007 Apr 4;334(1-2):1-14. doi: 10.1016/j.ijpharm.2007.01.028. Epub 2007 Jan 21.
2
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Cholesterol reduction using psyllium husks - do gastrointestinal adverse effects limit compliance? Results of a specific observational study.使用车前子壳降低胆固醇——胃肠道不良反应会限制依从性吗?一项特定观察性研究的结果
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Randomised clinical trial: dried plums (prunes) vs. psyllium for constipation.随机临床试验:干梅(西梅干)与车前子壳治疗便秘的比较。
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Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial.车前草和瓜尔豆膳食补充剂对高血压超重患者血压控制的不同影响:一项为期六个月的随机临床试验。
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Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients.麦麸和容积性泻药卵叶车前对老年住院患者地高辛生物利用度的影响。
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Dried plums, constipation and the irritable bowel syndrome.西梅干、便秘与肠易激综合征
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Laxative drug products for over-the-counter human use; psyllium ingredients in granular dosage forms. Final rule.用于非处方人类使用的泻药产品;颗粒剂型中的车前草成分。最终规则。
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