壳六糖诱导白色念珠菌的酵母增殖。

Chitohexose induce the yeast proliferation of Candida albicans.

作者信息

Kadowaki Osamu, Ogasawara Ayako, Watanabe Toshihiko, Mikami Takeshi, Matsumoto Tatsuji, Misawa Yoshitomo, Matahira Yoshiharu, Sakai Kazuo

机构信息

Department of Microbiology, Tohoku Pharmaceutical University, 4-4-1, Komatsushima, Aoba-ku, Sendai 981-8558, Japan.

出版信息

Biol Pharm Bull. 2007 Mar;30(3):583-4. doi: 10.1248/bpb.30.583.

DOI:10.1248/bpb.30.583

PMID:17329861

Abstract

Candida albicans generally grows in the hyphae form in RPMI1640 medium. Chitohexose (COS-6) induced the yeast form of C. albicans dose-dependently under this condition. When COS-6 was exposed to C. albicans, yeast proliferation was observed 6 h after starting the incubation. When we observed the growth form of C. albicans cultured with COS-6, yeast proliferation was observed at log-phase. These results showed that COS-6 was useful for the yeast form inducer of C. albicans.

摘要

白色念珠菌通常在RPMI1640培养基中以菌丝形式生长。在此条件下，壳六糖（COS-6）能剂量依赖性地诱导白色念珠菌转变为酵母形态。当将COS-6作用于白色念珠菌时，培养开始6小时后可观察到酵母增殖。当我们观察用COS-6培养的白色念珠菌的生长形态时，在对数期观察到酵母增殖。这些结果表明，COS-6可作为白色念珠菌酵母形态的诱导剂。