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还原型烟酰胺腺嘌呤二核苷酸、腺嘌呤核苷酸和2-氧代戊二酸对甲基营养菌中柠檬酸合酶活性的调节

Regulation of citrate synthase activity in methylotrophs by reduced nicotinamide-adenine dinucleotide, adenine nucleotides and 2-oxoglutarate.

作者信息

Colby J, Zatman L J

出版信息

Biochem J. 1975 Jul;150(1):141-4. doi: 10.1042/bj1500141.

Abstract

Citrate synthase from two typical facultative methylotrophs, but not from four obligate methylotrophs or from two restricted facultative methylotrophs, is inhibited by 0.1 mM-NADH. ATP or ADP (both at 10mM) inhibits all the citrate synthases, whereas 2-oxoglutarate (10mM) inhibits those from only three of the eight methylotrophs.

摘要

来自两种典型兼性甲基营养菌的柠檬酸合酶会受到0.1 mM-NADH的抑制,但来自四种专性甲基营养菌或两种受限兼性甲基营养菌的柠檬酸合酶则不会。ATP或ADP(均为10 mM)会抑制所有的柠檬酸合酶,而2-氧代戊二酸(10 mM)仅抑制八种甲基营养菌中三种的柠檬酸合酶。

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本文引用的文献

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The inhibition of lemon citrate-condensing enzyme by ATP.ATP对柠檬酸盐缩合酶的抑制作用。
Biochim Biophys Acta. 1966 Oct 17;128(1):190-2. doi: 10.1016/0926-6593(66)90158-5.
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The nitrogen nutrition of soil and herbage coryneform bacteria.土壤与草本棒状杆菌的氮素营养
J Appl Bacteriol. 1969 Sep;32(3):338-47. doi: 10.1111/j.1365-2672.1969.tb00981.x.
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The inhibition of citrate synthase by adenosine triphosphate.
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