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还原型烟酰胺腺嘌呤二核苷酸、腺嘌呤核苷酸和2-氧代戊二酸对甲基营养菌中柠檬酸合酶活性的调节

Regulation of citrate synthase activity in methylotrophs by reduced nicotinamide-adenine dinucleotide, adenine nucleotides and 2-oxoglutarate.

作者信息

Colby J, Zatman L J

出版信息

Biochem J. 1975 Jul;150(1):141-4. doi: 10.1042/bj1500141.

DOI:10.1042/bj1500141
PMID:173299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1165715/
Abstract

Citrate synthase from two typical facultative methylotrophs, but not from four obligate methylotrophs or from two restricted facultative methylotrophs, is inhibited by 0.1 mM-NADH. ATP or ADP (both at 10mM) inhibits all the citrate synthases, whereas 2-oxoglutarate (10mM) inhibits those from only three of the eight methylotrophs.

摘要

来自两种典型兼性甲基营养菌的柠檬酸合酶会受到0.1 mM-NADH的抑制，但来自四种专性甲基营养菌或两种受限兼性甲基营养菌的柠檬酸合酶则不会。ATP或ADP（均为10 mM）会抑制所有的柠檬酸合酶，而2-氧代戊二酸（10 mM）仅抑制八种甲基营养菌中三种的柠檬酸合酶。

相似文献

1
Regulation of citrate synthase activity in methylotrophs by reduced nicotinamide-adenine dinucleotide, adenine nucleotides and 2-oxoglutarate.还原型烟酰胺腺嘌呤二核苷酸、腺嘌呤核苷酸和2-氧代戊二酸对甲基营养菌中柠檬酸合酶活性的调节
Biochem J. 1975 Jul;150(1):141-4. doi: 10.1042/bj1500141.
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Citrate synthase.
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Evidence of isosteric and allosteric nucleotide inhibition of citrate synthease from multiple-inhibition studies.来自多重抑制研究的关于柠檬酸合酶的等排体和别构核苷酸抑制作用的证据。
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The interactions of adenylates with allosteric citrate synthase.
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Regulation of citrate synthase activity of Saccharomyces cerevisiae.酿酒酵母柠檬酸合酶活性的调控
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引用本文的文献

1
Methane-oxidizing microorganisms.甲烷氧化微生物
Microbiol Rev. 1981 Dec;45(4):556-90. doi: 10.1128/mr.45.4.556-590.1981.
2
Specialist phototrophs, lithotrophs, and methylotrophs: a unity among a diversity of procaryotes?专性光合营养菌、无机营养菌和甲基营养菌：原核生物多样性中的统一体？
Bacteriol Rev. 1977 Jun;41(2):419-48. doi: 10.1128/br.41.2.419-448.1977.

本文引用的文献

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Regulation of citrate synthase activity by alpha-ketoglutarate. Metabolic and taxonomic significance.α-酮戊二酸对柠檬酸合酶活性的调节。代谢及分类学意义。
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The inhibition of lemon citrate-condensing enzyme by ATP.ATP对柠檬酸盐缩合酶的抑制作用。
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ATP controlled acetoacetate and citrate synthesis by rat liver mitochondria oxidising palmitoyl-carnitine, and the inhibition of citrate synthase by ATP.ATP 控制大鼠肝脏线粒体氧化棕榈酰肉碱时乙酰乙酸和柠檬酸的合成，以及 ATP 对柠檬酸合酶的抑制作用。
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Kinetics of regulatory enzymes: effect of adenosine triphosphate on yeast citrate synthase.调节酶的动力学：三磷酸腺苷对酵母柠檬酸合酶的影响
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Enzymes of the mandelate pathway in Bacterium N.C.I.B. 8250.细菌N.C.I.B. 8250中扁桃酸途径的酶
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Enrichment, isolation and some properties of methane-utilizing bacteria.甲烷利用菌的富集、分离及某些特性
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The nitrogen nutrition of soil and herbage coryneform bacteria.土壤与草本棒状杆菌的氮素营养
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Regulation of alpha-ketoglutarate dehydrogenase formation in Escherichia coli.大肠杆菌中α-酮戊二酸脱氢酶形成的调控
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The inhibition of citrate synthase by adenosine triphosphate.
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Trimethylamine metabolism in obligate and facultative methylotrophs.专性和兼性甲基营养菌中的三甲胺代谢
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