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接受初次全髋关节置换术的肥胖女性和男性的预后差异。

Differences in outcomes of obese women and men undergoing primary total hip arthroplasty.

作者信息

Lübbeke Anne, Stern Richard, Garavaglia Guido, Zurcher Line, Hoffmeyer Pierre

机构信息

Orthopaedic Surgery Service, University Hospital of Geneva, Geneva, Switzerland.

出版信息

Arthritis Rheum. 2007 Mar 15;57(2):327-34. doi: 10.1002/art.22542.

Abstract

OBJECTIVE

To evaluate the effect of obesity on the incidence of main complications (infection, dislocation, and revision), functional outcome, and patient satisfaction 5 years after primary total hip arthroplasty (THA), and to determine whether results differ between obese women and men.

METHODS

We conducted a hospital-based prospective cohort study including patients who underwent primary THA (2,495 hips) between 1996 and 2005. We used rates and rate ratios to compare the incidence of main complications in obese and nonobese patients, and we stratified the data for sex. Functional outcome was measured using the Harris Hip Score and Western Ontario and McMaster Universities Osteoarthritis Index.

RESULTS

The adjusted incidence rate ratio for infection (obese versus nonobese) was 4.4 (95% confidence interval [95% CI] 1.8, 10.8). Obesity substantially increased the infection rate in women (incidence rate ratio comparing obese with nonobese women 16.1; 95% CI 3.4, 75.7), whereas obesity appeared to have no effect in men (incidence rate ratio 1.0; 95% CI 0.2, 5.3). The adjusted incidence rate ratio for dislocation (obese versus nonobese) was 2.4 (95% CI 1.4, 4.2), with a higher rate increase in obese women. A total of 817 patients had a 5-year clinical followup visit. Functional outcome and satisfaction were slightly lower in obese women partly due to higher complication rates. No difference was seen in men.

CONCLUSION

Primary THA is a successful intervention in obese patients, but physician and patient must be aware of increased complications, particularly in women.

摘要

目的

评估肥胖对初次全髋关节置换术(THA)后5年主要并发症(感染、脱位和翻修)发生率、功能结局及患者满意度的影响,并确定肥胖女性和男性的结果是否存在差异。

方法

我们进行了一项基于医院的前瞻性队列研究,纳入了1996年至2005年间接受初次THA(2495髋)的患者。我们使用发生率和率比来比较肥胖和非肥胖患者主要并发症的发生率,并按性别对数据进行分层。使用Harris髋关节评分和西安大略和麦克马斯特大学骨关节炎指数来测量功能结局。

结果

感染的校正发生率比(肥胖与非肥胖)为4.4(95%置信区间[95%CI]1.8,10.8)。肥胖显著增加了女性的感染率(肥胖与非肥胖女性的发生率比为16.1;95%CI 3.4,75.7),而肥胖对男性似乎没有影响(发生率比为1.0;95%CI 0.2,5.3)。脱位的校正发生率比(肥胖与非肥胖)为2.4(95%CI 1.4,4.2),肥胖女性的发生率增加更高。共有817例患者进行了5年的临床随访。肥胖女性的功能结局和满意度略低,部分原因是并发症发生率较高。男性未见差异。

结论

初次THA对肥胖患者是一种成功的干预措施,但医生和患者必须意识到并发症增加,尤其是女性。

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