Romanenko Svetlana A, Volobouev Vitaly T, Perelman Polina L, Lebedev Vladimir S, Serdukova Natalya A, Trifonov Vladimir A, Biltueva Larisa S, Nie Wenhui, O'Brien Patricia C M, Bulatova Nina Sh, Ferguson-Smith Malcolm A, Yang Fengtang, Graphodatsky Alexander S
Institute of Cytology and Genetics, SB RAS, Novosibirsk, 630090, Russia.
Chromosome Res. 2007;15(3):283-97. doi: 10.1007/s10577-007-1124-3. Epub 2007 May 10.
The evolutionary success of rodents of the superfamily Muroidea makes this taxon the most interesting for evolution studies, including study at the chromosomal level. Chromosome-specific painting probes from the Chinese hamster and the Syrian (golden) hamster were used to delimit homologous chromosomal segments among 15 hamster species from eight genera: Allocricetulus, Calomyscus, Cricetulus, Cricetus, Mesocricetus, Peromyscus, Phodopus and Tscherskia (Cricetidae, Muroidea, Rodentia). Based on results of chromosome painting and G-banding, comparative maps between 20 rodent species have been established. The integrated maps demonstrate a high level of karyotype conservation among species in the Cricetus group (Cricetus, Cricetulus, Allocricetulus) with Tscherskia as its sister group. Species within the genera Mesocricetus and Phodopus also show a high degree of chromosomal conservation. Our results substantiate many of the conclusions suggested by other data and strengthen the topology of the Muroidea phylogenetic tree through the inclusion of genome-wide chromosome rearrangements. The derivation of the muroids karyotypes from the putative ancestral state involved centric fusions, fissions, addition of heterochromatic arms and a great number of inversions. Our results provide further insights into the karyotype relationships of all species investigated.
鼠总科啮齿动物在进化上的成功使得这个分类单元成为进化研究中最有趣的对象，包括在染色体水平上的研究。来自中国仓鼠和叙利亚（金黄）仓鼠的染色体特异性涂染探针被用于界定8个属的15种仓鼠之间的同源染色体片段，这些属包括：Allocricetulus、Calomyscus、Cricetulus、Cricetus、Mesocricetus、Peromyscus、Phodopus和Tscherskia（仓鼠科，鼠总科，啮齿目）。基于染色体涂染和G带分析结果，已建立了20种啮齿动物之间的比较图谱。整合后的图谱显示，仓鼠属组（Cricetus、Cricetulus、Allocricetulus）的物种与Tscherskia作为其姐妹群之间具有高度的核型保守性。Mesocricetus属和Phodopus属内的物种也表现出高度的染色体保守性。我们的结果证实了其他数据所提出的许多结论，并通过纳入全基因组染色体重排强化了鼠总科系统发育树的拓扑结构。从假定的祖先状态推导鼠类核型涉及着丝粒融合、裂变、异染色质臂的添加以及大量倒位。我们的结果为所有研究物种的核型关系提供了进一步的见解。
