Bogas Mónica, Afonso Maria do Carmo, Araújo Domingos
Serviço de Reumatologia do Centro Hospitalar do Alto Minho, Ponte de Lima.
Acta Reumatol Port. 2006 Oct-Dec;31(4):349-54.
Anaemia is a common clinical feature in patients with rheumatoid arthritis and the coexistence of blood loss may not show an obvious iron deficiency anaemia. The cause may be a cancer or other reason for gastrointestinal bleeding that could be underestimated for being explained as associated with the chronic rheumatic disease. Although less described than gastroduodenal lesions, small bowel damage of non-steroidal anti-inflammatory drugs, used in the treatment of rheumatic diseases, are more common than previously thought. The authors describe a clinical case paradigmatic of the difficulties that may appear in the approach of anaemia in a patient with a chronic rheumatic disease and discuss some features of intestinal toxicity of nonsteroidal anti-inflammatory drugs.
贫血是类风湿性关节炎患者常见的临床特征，失血并存时可能不会表现出明显的缺铁性贫血。其原因可能是癌症或其他导致胃肠道出血的原因，这些原因可能因被解释为与慢性风湿性疾病相关而被低估。尽管与胃十二指肠病变相比描述较少，但用于治疗风湿性疾病的非甾体抗炎药对小肠的损害比以前认为的更为常见。作者描述了一个临床病例，该病例典型地体现了慢性风湿性疾病患者在贫血诊治过程中可能出现的困难，并讨论了非甾体抗炎药肠道毒性的一些特征。
