[非甾体抗炎药对肠道的损害]
[Intestinal damage by non-steroidal anti-inflammatory drugs].
作者信息
Rocha Ramírez José Luis, Parrado Montaño Javier Walter, Rojas Illanes Moisés, Sierra Montenegro Ernesto, Soto Quirino René, Manuel Rivero José
机构信息
Servicio de Cirugía de Colon y Recto, Hospital de Especialidades CMN Siglo XXI IMSS, Av. Cuauhtémoc No. 330, Col. Doctores, C.P. 06700, México, DF.
出版信息
Rev Gastroenterol Mex. 2007 Jan-Mar;72(1):43-6.
BACKGROUND
Nonsteroidal antiinflammatory Drugs (NSAIDS) are the most widely prescribed medication in the world, with a high complication rate including gastrointestinal damage.
OBJECTIVE
To present two clinical cases of intestinal damage associated to the chronic ingestion of NSAIDs.
METHOD
A clinical case with inflammatory bowel disease and jejunum enteropathy and another case associated with clinical symptoms of digestive hemorrhage and endoscopic demostration of ulcers in the right colon.
CONCLUSION
Patients with previous ingestion of NSAIDs presenting diarrhea, gastrointestinal bleeding, malnutrition or anemia need to discard intestinal damage.
背景
非甾体抗炎药（NSAIDs）是世界上处方量最大的药物，其并发症发生率很高，包括胃肠道损伤。
目的
介绍两例与长期服用NSAIDs相关的肠道损伤临床病例。
方法
一例患有炎症性肠病和空肠病变，另一例伴有消化性出血的临床症状且结肠镜检查显示右结肠有溃疡。
结论
既往服用过NSAIDs的患者若出现腹泻、胃肠道出血、营养不良或贫血，需要排除肠道损伤。
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