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沙特阿拉伯西部地区青春期女学生维生素D缺乏性佝偻病的患病率

Prevalence of vitamin D deficiency rickets in adolescent school girls in Western region, Saudi Arabia.

作者信息

Siddiqui Aisha M, Kamfar Hayat Z

机构信息

Department of Medicine, King Abdulaziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia.

出版信息

Saudi Med J. 2007 Mar;28(3):441-4.

PMID:17334476
Abstract

OBJECTIVE

To determine the prevalence of vitamin D deficiency rickets among female adolescents and assess its relation to calcium intake and sun exposure.

METHODS

Four hundred and thirty-three school girls between 12-15 years old were selected randomly from different schools in Jeddah, between October 200--February 2004. We identified symptoms of rickets and determined the dietary habits and sun exposure habits, and laboratory investigations were also carried out.

RESULTS

It was found that, out of 433 cases, 350 (81%) had low vitamin D levels. Approximately 40% had very low levels of vitamin D and 61% were asymptomatic. Most of the symptoms were non specific. There was a positive correlation between low calcium in the diet and less sun exposure to low levels of vitamin D. Approximately 96% had normal serum phosphate, 89% had normal serum calcium, and 40% had normal serum alkaline phosphatase levels.

CONCLUSION

Vitamin D deficiency is common among adolescent females in Jeddah, Saudi Arabia. Cases are missed due to lack of symptoms in most cases and normal bone chemistry. Serum vitamin D level should be carried out in suspected cases. Health and nutritional education should be encouraged in schools. Focusing on the importance of adequate milk intake and sun exposure should be given a priority in any health education program.

摘要

目的

确定吉达市女性青少年维生素D缺乏性佝偻病的患病率,并评估其与钙摄入量和日照的关系。

方法

2000年10月至2004年2月期间,从吉达市不同学校随机选取433名12至15岁的女学生。我们识别佝偻病症状,确定饮食习惯和日照习惯,并进行实验室检查。

结果

发现433例中,350例(81%)维生素D水平较低。约40%维生素D水平极低,61%无症状。大多数症状不具特异性。饮食中钙含量低和日照少与维生素D水平低呈正相关。约96%血清磷酸盐正常,89%血清钙正常,40%血清碱性磷酸酶水平正常。

结论

沙特阿拉伯吉达市青少年女性中维生素D缺乏很常见。多数病例因无症状和骨生化指标正常而漏诊。疑似病例应检测血清维生素D水平。应在学校鼓励开展健康和营养教育。在任何健康教育项目中,应优先强调充足摄入牛奶和日照的重要性。

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