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[The importance of essential fatty acids and the effect of trans fatty acids in human milk on fetal and neonatal development].

作者信息

Tinoco Sandra Manzato Barboza, Sichieri Rosely, Moura Anibal Sanchez, Santos Flávia da Silva, Carmo Maria das Graças Tavares do

机构信息

Departamento de Ciências Fisiológicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil.

出版信息

Cad Saude Publica. 2007 Mar;23(3):525-34. doi: 10.1590/s0102-311x2007000300011.

DOI:10.1590/s0102-311x2007000300011
PMID:17334567
Abstract

Breastfeeding has a major impact on public health, since human breast milk is the best food for infants up to six months of age. The lipid fraction in human milk is the main source of energy for the infant and supplies essential nutrients such as fat-soluble vitamins and polyunsaturated fatty acids (PUFA). Essential fatty acids (EFA), specifically linoleic acid (LA, 18:2n-6) and alpha-linolenic acid (ALA, 18:3n-3), are precursors of long-chain polyunsaturated fatty acids (LC-PUFA), including docosahexaenoic (DHA) and arachidonic (ARA) acids. Quality of lipids in secreted milk is precisely related to maternal ingestion. LC-PUFAs protect against allergy and infection and are important for visual and cognitive development in infancy. Industrial food processing has introduced the trans fatty acids (TFA) among the nutrients available to the population. TFA can interfere with the metabolism of essential fatty acids by decreasing LC-PUFA synthesis. It is thus important to raise population awareness on the importance of adequate PUFA consumption and reduced TFA intake during prenatal and postnatal development.

摘要

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