da Costa Roseli de Souza Santos, Santos Flavia da Silva, da Conceição Felipe Domingues, Saunders Claudia, Sardinha Fatima Lúcia de Carvalho, Chaves Célia Regina Moutinho de Miranda, do Carmo Maria da Graças Tavares
Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Lipids. 2011 Jun;46(6):537-43. doi: 10.1007/s11745-011-3547-z. Epub 2011 Mar 16.
The purpose of this study was to determine the levels of trans-octadecenoic acid (C18:1-trans) and trans-isomers of linoleic acid (18:2-trans), as well as long-chain polyunsaturated fatty acids (LC-PUFA), in the plasma from infants of adolescent mothers at 3 months of age, exclusively breastfed, and the relationship with the levels of the same isomers in plasma and milk of the mothers. Samples of blood and mature milk were obtained from 49 healthy adolescent mothers and their exclusively breastfed infants treated at the Instituto Fernandes Figueira-Fundação Oswaldo Cruz (IFF-FIOCRUZ) in Rio de Janeiro, Brazil. trans-Fatty acids (TFA) were analyzed by gas chromatography. The results of this study showed low levels of TFA in milk (1.53%), maternal plasma (0.50%), and plasma of infants (0.74%). The results show that, although TFA have been found in the plasma of the studied infants, the LC-PUFA levels are kept within normal limits. No association between TFA presence and parameters of nutritional status of the infants was observed, probably due to the low levels of these fatty acids found in this study.
本研究的目的是测定3月龄纯母乳喂养的青春期母亲所生婴儿血浆中的反式十八碳烯酸(C18:1 - 反式)、亚油酸反式异构体(18:2 - 反式)以及长链多不饱和脂肪酸(LC - PUFA)的水平,以及这些水平与母亲血浆和乳汁中相同异构体水平的关系。从巴西里约热内卢的费尔南德斯·菲格雷拉研究所 - 奥斯瓦尔多·克鲁兹基金会(IFF - FIOCRUZ)接受治疗的49名健康青春期母亲及其纯母乳喂养的婴儿中采集了血液和成熟乳汁样本。通过气相色谱法分析反式脂肪酸(TFA)。本研究结果显示,乳汁(1.53%)、母亲血浆(0.50%)和婴儿血浆(0.74%)中的TFA水平较低。结果表明,尽管在所研究婴儿的血浆中发现了TFA,但LC - PUFA水平保持在正常范围内。未观察到TFA的存在与婴儿营养状况参数之间的关联,这可能是由于本研究中发现的这些脂肪酸水平较低。