Weir I H, Müller N L, Chiles C, Godwin J D, Lee S H, Kullnig P
Department of Radiology, University of British Columbia, Vancouver.
Can Assoc Radiol J. 1992 Feb;43(1):31-4.
Radiographs and computed tomography (CT) scans of the chest were reviewed for 10 patients with pathologically proven Wegener's granulomatosis. The CT scans revealed multiple pulmonary nodules in seven patients and a single nodule in one. The nodules ranged in diameter from 2 mm to 7 cm, and most had irregular margins. All of the nodules larger than 2 cm in diameter showed evidence of cavitation in the CT scans. Additional CT findings included associated areas of consolidation (in two patients), pleural thickening (in two) and pleural effusion (in two). Chest radiographs were available for eight patients, and the CT scans contributed information additional to that available from the radiographs for seven of these. In one patient lung nodules were visible in the CT scans but could not be distinguished from surrounding areas of consolidation in the chest radiographs. CT revealed additional nodules in five of the six patients in whom multiple nodules were seen in chest radiographs and in one of these also revealed cavitation tht was not visible in plain radiographs. CT excluded the possibility of a nodule that was suspected from the chest radiographs in a patient who had been treated previously for Wegener's granulomatosis. The authors conclude that Wegener's granulomatosis is characterized in CT scans by multiple nodules with irregular margins and by cavitation in nodules larger than 2 cm in diameter. CT may also demonstrate nodules and cavitation not apparent in radiographs.
对10例经病理证实为韦格纳肉芽肿病患者的胸部X光片和计算机断层扫描（CT）进行了回顾。CT扫描显示，7例患者有多个肺结节，1例有单个结节。结节直径从2毫米到7厘米不等，多数边缘不规则。所有直径大于2厘米的结节在CT扫描中均显示有空洞形成。CT的其他表现包括合并实变区域（2例）、胸膜增厚（2例）和胸腔积液（2例）。8例患者有胸部X光片，其中7例患者CT扫描提供了X光片之外的额外信息。1例患者的肺结节在CT扫描中可见，但在胸部X光片中无法与周围实变区域区分开来。6例胸部X光片显示有多个结节的患者中，5例CT发现了额外的结节，其中1例还显示出X光片上不可见的空洞。CT排除了1例曾接受过韦格纳肉芽肿病治疗患者胸部X光片上疑似结节的可能性。作者得出结论，韦格纳肉芽肿病在CT扫描中的特征为多个边缘不规则的结节以及直径大于2厘米的结节出现空洞。CT还可能显示出X光片中不明显的结节和空洞。
