Li Jiakai, Li Chuangui, Li Jiaojiao
Department of Radiology, The Hainan Branch of The Chinese PLA General Hospital, Sanya, Hainan 572013, P.R. China.
Department of Radiology, The Chinese PLA General Hospital, Beijing 100853, P.R. China.
Exp Ther Med. 2018 Jul;16(1):413-419. doi: 10.3892/etm.2018.6154. Epub 2018 May 11.
The aim of the present study was to investigate the computed tomography (CT) manifestations of Wegener granulomatosis (WG) in the chest and potential reasons for misdiagnosis. Conventional CT scans and clinical data of 45 patients with WG were retrospectively analyzed. Patients typically presented with multiple system involvement, primarily in the upper and lower respiratory tract. The incidence of thoracic involvement was 75.56% (34/45). Radiographic features were varied between cases in the present study, with the most common features being numerous cavitary nodules and masses in the lungs. Cavitations were usually irregular, with uneven wall thickness, partial centrality, fuzzy inner edges and piecemeal necrosis. These results indicate that WG typically has multiple system involvement, with the chest being most prominent. Multiple variable-sized cavitary nodules with irregular edges and piecemeal necrosis were the most notable features revealed using CT scanning; however, in order to give a definitive diagnosis, biopsies should be performed.
本研究的目的是探讨韦格纳肉芽肿(WG)的胸部计算机断层扫描(CT)表现及误诊的潜在原因。回顾性分析了45例WG患者的常规CT扫描和临床资料。患者通常表现为多系统受累,主要累及上、下呼吸道。胸部受累的发生率为75.56%(34/45)。本研究中各病例的影像学特征各不相同,最常见的特征是肺部出现大量空洞性结节和肿块。空洞通常不规则,壁厚不均匀,部分位于中央,内缘模糊,呈碎片状坏死。这些结果表明,WG通常多系统受累,胸部受累最为突出。CT扫描显示,边缘不规则且呈碎片状坏死的多个大小不一的空洞性结节是最显著的特征;然而,为了做出明确诊断,应进行活检。