正常受试者中合成促肾上腺皮质激素（β1-24-促皮质素）抗原性的研究（作者译）
[Studies on the antigenicity of synthetic ACTH (beta1-24-corticotropin) in normal subjects (author's transl)].
作者信息
Mauff G, Weinheimer B, Urbaschek B
出版信息
Arzneimittelforschung. 1975 Nov;25(11):1823-6.
PMID:173352
Abstract
9 healthy volunteers were subjected to a 3-week treatment with synthetic ACTH. Antibody response against beta1-24-corticotropin (Synacthen) was tested by passive transfer in the Prausnitz-Küstner reaction, complement fixation, passive hemagglutination and agar-gel diffusion. Failure of the healthy persons to produce reaginic or non-reaginic antibodies is compared titerature.
摘要
9名健康志愿者接受了为期3周的合成促肾上腺皮质激素治疗。通过普劳斯尼茨-屈斯特纳反应中的被动转移、补体结合、被动血凝和琼脂凝胶扩散试验，检测了针对β1-24-促肾上腺皮质激素（辛纳科特）的抗体反应。将健康人未能产生反应素或非反应素抗体的情况与文献进行了比较。
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