Młynarczyk Grazyna, Młynarczyk Andrzej, Szymanek Ksenia, Luczak Mirosław
Katedra i Zakład Mikrobiologii Lekarskiej AM w Warszawie.
Med Dosw Mikrobiol. 2006;58(3):183-90.
The group of 50 clinical MRSA strains resistant to MLS-B was examined for the presence of ermA, ermB, ermC, msrA/B genes by using PCR. Gene ermA was found in 43 strains (86%). 20 of ermA strains demonstrated inducible whereas 23 constitutive type of expression. The gene ermC was present in 15 of examined MRSA strains (30%). The expression of the gene was inducible in the case of 9 and constitutive in the case of 6 of the strains. The msrA/B gene was present in the case of 5 strains (10%). The ermB gene was not detected among the investigated strains.
通过聚合酶链反应（PCR）检测了50株对大环内酯-林可酰胺-链阳菌素B（MLS-B）耐药的临床耐甲氧西林金黄色葡萄球菌（MRSA）菌株中ermA、ermB、ermC、msrA/B基因的存在情况。在43株菌株（86%）中发现了ermA基因。其中20株ermA基因菌株表现为诱导型，23株为组成型表达。在所检测的MRSA菌株中有15株（30%）存在ermC基因。该基因在9株菌株中表现为诱导型表达，在6株菌株中为组成型表达。5株菌株（10%）中存在msrA/B基因。在所研究的菌株中未检测到ermB基因。
