Tanaka Toyohiko, Takahashi Masashi, Nitta Norihisa, Furukawa Akira, Andoh Akira, Saito Yasuharu, Fujiyama Yoshihide, Murata Kiyoshi
Department of Radiology, Shiga University of Medical Science, Tsukinowa-cho, Seta, Otsu, Shiga 520-2192, Japan.
Digestion. 2006;74(3-4):199-205. doi: 10.1159/000100504. Epub 2007 Mar 6.
We developed an Ultraflex-type stent by knitting polylactic acid monofilaments. The purpose of this study was to evaluate the stent's clinical usefulness for treating benign stenoses in the gastrointestinal tract. The radial force of the biodegradable stent was compared with those of commercially available metallic stents. The measured radial force of the new biodegradable stent was higher than that of commercially available metallic stents. The biodegradable stents were applied in 2 patients with benign gastrointestinal stenoses. The first patient was a 19-year-old female with esophageal stenosis, due to drinking of caustic potash in an attempt to commit suicide. The second patient was a 75-year-old male who had a stenosis at the anastomotic site after esophageal cancer resection. In both cases, the placement of the stent was performed successfully, and the patients' complaints improved immediately after stent placement. There were no complications during stent placement. The stenosis had not recurred at the six-month follow-up examination. In conclusion, the newly developed biodegradable stents were useful in treating benign stenoses of the alimentary tract.
我们通过编织聚乳酸单丝研制出一种超弹性型支架。本研究的目的是评估该支架在治疗胃肠道良性狭窄方面的临床实用性。将这种可生物降解支架的径向力与市售金属支架的径向力进行了比较。新的可生物降解支架测得的径向力高于市售金属支架。该可生物降解支架应用于2例胃肠道良性狭窄患者。首例患者为一名19岁女性，因企图自杀饮用苛性钾导致食管狭窄。第二例患者是一名75岁男性，在食管癌切除术后吻合口处出现狭窄。在这两个病例中，支架均成功置入，患者的症状在支架置入后立即得到改善。支架置入过程中无并发症发生。在六个月的随访检查中，狭窄未复发。总之，新研制的可生物降解支架在治疗消化道良性狭窄方面是有用的。
