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泊沙康唑治疗一名糖尿病控制良好的男性创伤后雅致犁头霉鼻眶接合菌病。

Posaconazole treatment for Apophysomyces elegans rhino-orbital zygomycosis following trauma for a male with well-controlled diabetes.

作者信息

Ferguson T D, Schniederjan S D, Dionne-Odom J, Brandt M E, Rinaldi M G, Nolte F S, Langston A, Zimmer S M

机构信息

Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

J Clin Microbiol. 2007 May;45(5):1648-51. doi: 10.1128/JCM.00014-07. Epub 2007 Mar 7.

DOI:10.1128/JCM.00014-07
PMID:17344359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1865874/
Abstract

We report a case of rhino-orbital zygomycosis in a 43-year-old male with well-controlled diabetes mellitus. The patient initially received liposomal amphotericin B, but the infection continued to progress, so posaconazole treatment was begun and eventually led to the cure of his infection. The causative agent was identified as Apophysomyces elegans, an emerging cause of zygomycosis in immunocompetent hosts.

摘要

我们报告一例43岁男性的鼻眶接合菌病，该患者患有控制良好的糖尿病。患者最初接受脂质体两性霉素B治疗，但感染仍持续进展，因此开始使用泊沙康唑治疗，最终治愈了感染。病原体被鉴定为雅致犁头霉，这是免疫功能正常宿主中接合菌病的一种新出现的病因。

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Zygomycosis: the re-emerging fungal infection.接合菌病：再度出现的真菌感染
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