Bourke P, Castro P, Rabagliati R, Beltran C, Verdejo H, Winter J L, Bourge R C
Division de Enfermedades Cardiovasculares, Escuela de Medicina, Facultad de Medicina Pontificia Universidad Católica de Chile, Santiago, Chile.
Transpl Infect Dis. 2012 Oct;14(5):E56-9. doi: 10.1111/j.1399-3062.2012.00772.x. Epub 2012 Jul 31.
Aspergillosis and zygomycosis are life-threatening fungal infections in immunocompromised patients. We report a heart transplant recipient with an early pulmonary invasive aspergillosis successfully treated with association of voriconazole and caspofungin. Zygomycosis sinusitis, which was diagnosed while he still was on voriconazole therapy, was successfully treated with the use of combination antifungal therapy including liposomal amphotericin plus posaconazole and conservative surgical debridement.
曲霉病和接合菌病是免疫功能低下患者中危及生命的真菌感染。我们报告了一名心脏移植受者，其早期肺部侵袭性曲霉病通过伏立康唑和卡泊芬净联合治疗成功治愈。在他仍接受伏立康唑治疗时被诊断出的接合菌病鼻窦炎，通过使用包括脂质体两性霉素加泊沙康唑的联合抗真菌治疗和保守性手术清创术成功治愈。
