Bai Ji-Gang, Dang Cheng-Xue
Department of General Surgery, First Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2007 Feb;32(1):138-43.
To determine the clinical application of the new classification of adenocarcinoma of esophagogastric junction (AEG).
The data of cancer of distal esophagus, cancer of cardia, and proximal gastric cancer were reviewed. Clinicopathologic characteristics, surgical modes and survival were analyzed according to Siewert's standards.
Among the 203 patients that were up to the standard, 29 had adenocarcinoma of the distal esophagus (Type I), 80 had true carcinoma of cardia (Type II), and 94 had subcardial carcinoma (Type III). The 5-year survival rates of the 3 types of patients after the operation were 34% for Type I, 27.5% for Type II, and 24.5% for Type III (P<0.05). Further analysis of the patients with curative resection suggested there was no significant difference in the 5-year survival rates, with 37.5% for Type I, 34.5% for Type II, and 33.3% for Type III (P>0.05).
Difference has been found in the clinicopathologic characteristics of the 3 types of adenocarcinoma of the esophagogastric junction. The exact relation of the 3 types is still unknown. The TNM classification, complete tumor resection and the extent of lymph node metastasis are critical for the prognosis of the patients.
确定食管胃交界腺癌（AEG）新分类的临床应用。
回顾远端食管癌、贲门癌和近端胃癌的数据。根据Siewert标准分析临床病理特征、手术方式和生存率。
在符合标准的203例患者中，远端食管癌（I型）29例，真性贲门癌（II型）80例，贲门下癌（III型）94例。三种类型患者术后5年生存率分别为：I型34%，II型27.5%，III型24.5%（P<0.05）。对根治性切除患者的进一步分析表明，5年生存率无显著差异，I型为37.5%，II型为34.5%，III型为33.3%（P>0.05）。
食管胃交界部三种类型腺癌的临床病理特征存在差异。三种类型的确切关系尚不清楚。TNM分类、肿瘤完整切除及淋巴结转移范围对患者预后至关重要。
