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[217例不同实体脊柱转移瘤手术患者中原发肿瘤及受累脊柱节段区域的预后影响]

[The prognostic influence of primary tumour and region of the affected spinal segment in 217 surgical patients with spinal metastases of different entities].

作者信息

Ulmar B, Huch K, Kocak T, Catalkaya S, Naumann U, Gerstner S, Reichel H

机构信息

Orthopädische Universitätsklinik Ulm, RKU, Ulm, Germany.

出版信息

Z Orthop Ihre Grenzgeb. 2007 Jan-Feb;145(1):31-8. doi: 10.1055/s-2007-960506.

Abstract

AIM

A retrospective study to evaluate the prognostic influence of the primary tumour and the anatomic level of spinal metastases was carried out.

MATERIAL AND METHODS

Between January 1984 and May 2005, 217 patients were surgically treated because of spinal metastases. The prognostic influence for the survival was analysed for the entity of the primary tumour and the localisation of the spinal metastases.

RESULTS

The median survival of the study group was 8.0 months (range: 0-191.5 months). Mamma carcinoma was the most frequent primary tumour with 62 cases (28.6 %). The spinal level of the metastases did not influence the postoperative survival (p = 0.9058). The entity of the primary tumour showed a significant influence for the postoperative survival (p < 0.0001).

CONCLUSION

In spinal metastases, the entity of the primary tumour was of prognostic value; the localisation of the spinal metastases at different spinal levels did not influence the postoperative survival. Therefore, the evaluation of the primary tumour is mandatory for an estimation of the expected survival.

摘要

目的

开展一项回顾性研究,以评估原发肿瘤及脊柱转移瘤的解剖学水平对预后的影响。

材料与方法

1984年1月至2005年5月期间,217例因脊柱转移瘤接受手术治疗的患者。分析了原发肿瘤类型及脊柱转移瘤的位置对生存的预后影响。

结果

研究组的中位生存期为8.0个月(范围:0 - 191.5个月)。乳腺癌是最常见的原发肿瘤,共62例(28.6%)。转移瘤的脊柱水平不影响术后生存(p = 0.9058)。原发肿瘤类型对术后生存有显著影响(p < 0.0001)。

结论

在脊柱转移瘤中,原发肿瘤类型具有预后价值;不同脊柱水平的脊柱转移瘤位置不影响术后生存。因此,评估原发肿瘤对于估计预期生存至关重要。

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