Turnbull W H, Leeds A R, Edwards D G
Department of Nutrition and Dietetics, King's College London, University of London, UK.
Am J Clin Nutr. 1992 Feb;55(2):415-9. doi: 10.1093/ajcn/55.2.415.
Mycoprotein is a food produced by continuous fermentation of Fusarium graminearum (Schwabe). A previous metabolic study showed that mycoprotein decreased total and low-density-lipoprotein (LDL) cholesterol and increased high-density-lipoprotein (HDL) cholesterol. This study was undertaken to determine the effects of mycoprotein under free-living conditions. Two groups of subjects with slightly raised cholesterol concentrations participated in the 8-wk study. The experimental group was fed cookies containing mycoprotein and the control group was fed a nutrient-balanced cookie without mycoprotein. After 8 wk of treatment total cholesterol was reduced by 0.46 mmol/L in the control group and 0.95 mmol/L in the mycoprotein group, and LDL was reduced by 0.34 mmol/L in the control group and 0.84 mmol/L in the mycoprotein group. All analysis of variance differences were statistically significant. This study confirms the metabolic-study results and we are now relatively confident that mycoprotein exerts a beneficial effect on blood lipids.
真菌蛋白是由禾谷镰刀菌(施瓦贝)连续发酵生产的一种食物。之前的一项代谢研究表明,真菌蛋白可降低总胆固醇和低密度脂蛋白(LDL)胆固醇水平,并提高高密度脂蛋白(HDL)胆固醇水平。本研究旨在确定在自由生活条件下真菌蛋白的作用。两组胆固醇浓度略有升高的受试者参与了这项为期8周的研究。实验组食用含有真菌蛋白的饼干,对照组食用不含真菌蛋白的营养均衡饼干。治疗8周后,对照组的总胆固醇降低了0.46 mmol/L,真菌蛋白组降低了0.95 mmol/L;对照组的LDL降低了0.34 mmol/L,真菌蛋白组降低了0.84 mmol/L。所有方差分析差异均具有统计学意义。本研究证实了代谢研究的结果,我们现在相对确信真菌蛋白对血脂有有益作用。