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非心脏手术后与支架相关的心脏事件:药物洗脱支架与裸金属支架的比较

Stent-related cardiac events after non-cardiac surgery: drug-eluting stent vs. bare metal stent.

作者信息

Kim Hack-Lyoung, Park Kyung-Woo, Kwak Jae-Jin, Kim Yong-Seok, Sir Jung-Ju, Lee Sook-Jin, Lee Hae-Young, Chang Hyuk-Jae, Kang Hyun-Jae, Cho Young-Seok, Chung Woo-Young, Chae In-Ho, Choi Dong-Joo, Kim Hyo-Soo, Oh Byung-Hee, Park Young-Bae, Koo Bon-Kwon

出版信息

Int J Cardiol. 2008 Jan 24;123(3):353-4. doi: 10.1016/j.ijcard.2006.11.182. Epub 2007 Mar 8.

Abstract

For evaluation of post-operative stent associated cardiac events after drug-eluting stent (DES) implantation we analyzed data of 138 patients who underwent non-cardiac surgery after DES implantation and compared the data with those of 101 patients who underwent non-cardiac surgery after bare metal stent (BMS) implantation. Three patients (2.2%) in DES group developed post-operative cardiac events and none in BMS group (p=0.2). One patient died due to suspected stent thrombosis and the other two had myocardial infarction due to angiographically proven stent thrombosis. The time interval between stent implantation and surgery in those with cardiac events was 6, 264, and 367 days, respectively. Our data shows that peri-operative stent-related thrombotic complications can occur long after DES implantation and careful peri-operative monitoring for cardiac events is needed in patients receiving non-cardiac surgery after DES implantation.

摘要

为评估药物洗脱支架(DES)植入术后与支架相关的心脏事件,我们分析了138例DES植入术后接受非心脏手术患者的数据,并将这些数据与101例裸金属支架(BMS)植入术后接受非心脏手术患者的数据进行比较。DES组有3例患者(2.2%)发生术后心脏事件,BMS组无患者发生(p = 0.2)。1例患者因疑似支架血栓形成死亡,另外2例因血管造影证实的支架血栓形成发生心肌梗死。发生心脏事件患者的支架植入与手术之间的时间间隔分别为6天、264天和367天。我们的数据表明,DES植入术后很长时间仍可能发生围手术期与支架相关的血栓并发症,DES植入术后接受非心脏手术的患者需要对心脏事件进行仔细的围手术期监测。

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