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非心脏手术中药物洗脱支架血栓形成的风险。

The risk of drug-eluting stent thrombosis with noncardiac surgery.

作者信息

Brilakis Emmanouil S, Banerjee Subhash, Berger Peter B

机构信息

Dallas VA Medical Center, Dallas, TX 75216, USA.

出版信息

Curr Cardiol Rep. 2007 Sep;9(5):406-11. doi: 10.1007/BF02938368.

DOI:10.1007/BF02938368
PMID:17877936
Abstract

Patients in whom any kind of stent, particularly a drug-eluting stent (DES), was recently implanted are at risk for stent thrombosis when they undergo noncardiac surgery, even months or years after their implantation. The risk of DES thrombosis is likely decreased by delaying noncardiac surgery for as long as possible and continuing dual or at least single antiplatelet therapy in the perioperative period. Preoperative identification and close monitoring of patients with DES may allow prevention and prompt detection and treatment of this catastrophic complication.

摘要

近期植入任何类型支架(尤其是药物洗脱支架[DES])的患者,在接受非心脏手术时存在支架血栓形成的风险,即使在植入数月或数年之后。尽可能推迟非心脏手术并在围手术期持续进行双联或至少单联抗血小板治疗,可能会降低DES血栓形成的风险。术前识别并密切监测DES患者,可能有助于预防、及时发现并治疗这种灾难性并发症。

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本文引用的文献

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药物洗脱支架与冠状动脉血栓形成:生物学机制及临床意义
Circulation. 2007 Feb 27;115(8):1051-8. doi: 10.1161/CIRCULATIONAHA.106.675934.
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Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study.西罗莫司洗脱支架和紫杉醇洗脱支架在常规临床实践中的早期和晚期冠状动脉支架血栓形成:来自一项大型双机构队列研究的数据。
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