Furusato Bungo, Koff Stacey, McLeod David G, Sesterhenn Isabell A
Department of Genitourinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA.
J Clin Pathol. 2007 Mar;60(3):325-6. doi: 10.1136/jcp.2006.039222.
A 55-year-old African-American man with clinical stage T1c prostate cancer underwent prostatectomy. Non-caseating, epithelioid granulomata adjacent to the anterior fibromuscular stroma were found incidentally. The granulomata included Langhans giant cells with rare conchoidal bodies. The distribution of the granulomata was not that of non-specific granulomatous prostatitis centred around ducts and glands. By immunohistochemistry, the epithelioid cells were positive for angiotensin-converting enzyme. The histological appearance suggested sarcoidosis, which was confirmed by the clinical history. Four years earlier, the patient had been treated for sarcoidosis.
一名55岁的非裔美国男性，临床分期为T1c期前列腺癌，接受了前列腺切除术。术中偶然发现前纤维肌性基质旁有非干酪样上皮样肉芽肿。肉芽肿内可见朗汉斯巨细胞，伴有罕见的同心层状体。肉芽肿的分布并非以导管和腺体为中心的非特异性肉芽肿性前列腺炎的分布。免疫组织化学显示，上皮样细胞血管紧张素转换酶呈阳性。组织学表现提示结节病，临床病史证实了这一点。四年前，该患者曾接受过结节病治疗。
