Kotani K, Tachibana M, Takamasu K
Graduate School of Information Science and Technology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Methods Inf Med. 2007;46(2):179-85.
The objective of our study is to investigate extrinsic influences on heart rate variability using respiratory-phase domain analysis. Swallowing, coughing and vocalization (reading aloud and conversation) are adopted as extrinsic influences.
In this study, an instantaneous R-R interval (RRI) is sampled at each pi/10 rad of the respiratory phase and the data is divided into three subsets: a) respiration with event, b) one respiration after the event, and c) normal respiration. Then the mean waveforms of respiratory sinus arrhythmia (RSA) are calculated and compared.
It is found that swallowing induces tachycardia that recovers within one respiration. Coughing also induces tachycardia, but it does not recover within one respiration. Vocalization shortens the mean RRI, but the changing respiratory pattern due to vocalization has no statistically significant influence on the amplitude of RSA. Furthermore, it is found that the proposed method is effective for analyzing extrinsic influences on heart rate variability (HRV).
我们研究的目的是使用呼吸相位域分析来研究心率变异性的外在影响因素。吞咽、咳嗽和发声（朗读和对话）被用作外在影响因素。
在本研究中，在呼吸相位的每个π/10弧度处对瞬时R-R间期（RRI）进行采样，并将数据分为三个子集：a）伴有事件的呼吸，b）事件发生后的一次呼吸，c）正常呼吸。然后计算并比较呼吸性窦性心律不齐（RSA）的平均波形。
发现吞咽会诱发心动过速，且在一次呼吸内恢复。咳嗽也会诱发心动过速，但在一次呼吸内不会恢复。发声会缩短平均RRI，但发声引起的呼吸模式变化对RSA的幅度没有统计学上的显著影响。此外，发现所提出的方法对于分析心率变异性（HRV）的外在影响是有效的。
