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新生儿低钙血症性手足搐搦作为未被识别的母亲原发性甲状旁腺功能亢进的一种表现。

Hypocalcemic tetany in the newborn as a manifestation of unrecognized maternal primary hyperparathyroidism.

作者信息

Pieringer Herwig, Hatzl-Griesenhofer Margit, Shebl Omar, Wiesinger-Eidenberger Gabriele, Maschek Wilhelmine, Biesenbach Georg

机构信息

2nd Department of Medicine, General Hospital Linz, Linz, Austria.

出版信息

Wien Klin Wochenschr. 2007;119(3-4):129-31. doi: 10.1007/s00508-006-0748-1.

Abstract

Primary hyperparathyroidism (PHP) during pregnancy is a very rare event that increases maternal and perinatal morbidity and mortality. We present a case in which hypocalcemic tetany of the neonatal infant - caused by transient hypoparathyroidism in the child - finally revealed asymptomatic maternal PHP. An apparently healthy 30-year-old woman had an uneventful pregnancy and delivery. On the 15th postpartal day, the newborn developed hypocalcemic tetany. After receiving supplementation of calcium and vitamin D, the child developed without further pathological findings. Laboratory and radiological studies in the mother led to a diagnosis of maternal PHP. An adenoma of the right lower parathyroid gland was subsequently removed. The search for the cause of hypocalcemia in a newborn should not focus on the patient alone. Examining the apparently healthy mother and approaching the case in a multidisciplinary fashion may benefit both the child and the mother.

摘要

妊娠期间的原发性甲状旁腺功能亢进症(PHP)是一种非常罕见的情况,会增加孕产妇和围产期的发病率及死亡率。我们报告一例病例,其中新生儿的低钙性手足搐搦症(由患儿短暂性甲状旁腺功能减退引起)最终揭示了无症状的母亲患有PHP。一名看似健康的30岁女性怀孕和分娩过程顺利。产后第15天,新生儿出现低钙性手足搐搦症。在补充钙和维生素D后,患儿未出现进一步的病理表现。对母亲进行的实验室和影像学检查导致诊断为母亲患有PHP。随后切除了右下甲状旁腺的腺瘤。对新生儿低钙血症病因的查找不应仅关注患儿本身。检查看似健康的母亲并以多学科方式处理该病例可能对患儿和母亲都有益。

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