Tripathi Parimal, Tripathi Varsha, Naik Ronak J, Patel Jaimin M
Gujarat Cancer and Research Institute, Ahmedabad, India.
Indian Pediatr. 2007 Feb;44(2):123-7.
To study neurological outcome of Moya Moya disease treated surgically with Encephaloduroarteriosynengopsis (EDAS).
Prospective observational study.
Community and General with tertiary care facility.
Eight children diagnosed with Moya Moya disease by Magnetic Resonance Angiogramover 4 years of period were selected for EDAS. Children who were not able to sustain surgery excluded from study.
Treatment modality selected were surgery in form of EDAS. After surgery subjects were followed up for minimum of 2 year period to know neurological out come. Outcome was reported as poor, fair, good and excellent. No statistical analysis performed due to small sample size.
After surgery no episode of stroke or TIA was observed in any patient during 2 year follow up period and all patients are living without any new neurological deficit.
Long term outcome of EDAS is promising.
研究采用脑-硬脑膜-动脉血管融通术(EDAS)手术治疗烟雾病的神经学转归。
前瞻性观察性研究。
设有三级护理设施的社区及综合医院。
选取4年间通过磁共振血管造影诊断为烟雾病的8名儿童接受EDAS治疗。无法耐受手术的儿童被排除在研究之外。
选择的治疗方式为EDAS手术。术后对研究对象进行至少2年的随访以了解神经学转归。转归分为差、一般、良好和优秀。由于样本量小未进行统计学分析。
术后2年随访期间,所有患者均未发生中风或短暂性脑缺血发作(TIA),且均未出现任何新的神经功能缺损。
EDAS的长期疗效令人期待。