用于缓解胃癌所致恶性胃出口梗阻患者症状的自膨式金属支架
Self-expandable metallic stents for palliation of patients with malignant gastric outlet obstruction caused by stomach cancer.
作者信息
Kim Tae Oh, Kang Dae Hwan, Kim Gwang Ha, Heo Jeong, Song Geun Am, Cho Mong, Kim Dong Heon, Sim Mun Sup
机构信息
Department of Internal Medicine, Pusan National University College of Medicine, 1-10 Ami-dong, Soe-gu, Busan 602-739, Korea.
出版信息
World J Gastroenterol. 2007 Feb 14;13(6):916-20. doi: 10.3748/wjg.v13.i6.916.
AIM
To ascertain clinical outcome and complications of self-expandable metal stents for endoscopic palliation of patients with malignant obstruction of the gastrointestinal (GI) tract.
METHODS
A retrospective review was performed throughout August 2000 to June 2005 of 53 patients with gastric outlet obstruction caused by stomach cancer. All patients had symptomatic obstruction including nausea, vomiting, and decreased oral intake. All received self-expandable metallic stents.
RESULTS
Stent implantation was successful in all 53 (100%) patients. Relief of obstructive symptoms was achieved in 43 (81.1%) patients. No immediate stent-related complications were noted. Seventeen patients had recurrent obstruction (tumor ingrowth in 14 patients, tumor overgrowth in 1 patient, and partial distal stent migration in 2 patients). The mean survival was 145 d. Median stent patency time was 187 d.
CONCLUSION
Endoscopic placement of self-expandable metallic stents is a safe and effective treatment for the palliation of patients with inoperable malignant gastric outlet obstruction caused by stomach cancer.
目的
确定自膨式金属支架用于内镜下缓解胃肠道恶性梗阻患者症状的临床疗效及并发症。
方法
对2000年8月至2005年6月期间53例因胃癌导致胃出口梗阻的患者进行回顾性研究。所有患者均有包括恶心、呕吐及经口摄入量减少等症状性梗阻。所有患者均接受了自膨式金属支架治疗。
结果
53例（100%）患者支架植入均成功。43例（81.1%）患者梗阻症状得到缓解。未发现与支架相关的即刻并发症。17例患者出现复发性梗阻（14例肿瘤向内生长，1例肿瘤过度生长，2例远端支架部分移位）。平均生存期为145天。支架通畅的中位时间为187天。
结论
内镜下置入自膨式金属支架是治疗因胃癌导致无法手术的恶性胃出口梗阻患者的一种安全有效的姑息治疗方法。
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