Kern K B, Nelson J R, Norman S A, Milander M M, Hilwig R W
Department of Internal Medicine, University of Arizona College of Medicine, Tucson.
Chest. 1992 Feb;101(2):522-9. doi: 10.1378/chest.101.2.522.
Use of continuous transtracheal oxygen delivery systems combined with rhythmic chest compressions can provide excellent oxygenation and ventilation during cardiopulmonary resuscitation. However, occasional displacement of the transtracheal catheter results in life-threatening pneumomediastinal complications. We investigated using the pharyngeal lumen of a pharyngeal-tracheal lumened airway (PtL) as an alternative delivery system for continuous oxygen flow in 21 large mongrel dogs. Excellent ventilation was possible in anesthetized, apneic, and paralyzed dogs in normal sinus rhythm from the "bellows" effect of chest compressions. The hypercapnia and respiratory acidemia resulting from 5 min of complete apnea in ten dogs during normal sinus rhythm was readily corrected (p less than 0.01). In an additional 11 dogs, external chest compressions were performed and oxygen was delivered continuously via the PtL during 20 min of ventricular fibrillation. During this period of cardiac arrest, pH declined (7.38 +/- 0.01 vs 7.19 +/- 0.02; p less than 0.01), but PaCO2 (35 +/- 1 vs 38 +/- 3 mm Hg) and PaO2 (67 +/- 2 vs 68 +/- 3 mm Hg) were not significantly different from prearrest values. Successful resuscitation was achieved in 8 of 11 (73 percent) animals, which is similar to the results in historical controls with endotracheal intubation. No pneumomediastinal complications were seen with use of the PtL. We conclude that using the pharyngeal lumen of the PtL for continuous delivery of oxygen combined with external chest compressions can provide a safe and effective mode of oxygenation and ventilation during cardiac arrest.
在心肺复苏过程中,使用持续经气管输氧系统并结合有节律的胸部按压能够实现出色的氧合和通气。然而,经气管导管偶尔移位会导致危及生命的纵隔气肿并发症。我们在21只大型杂种犬身上研究了将咽-气管双腔气道(PtL)的咽腔用作持续氧气流的替代输送系统。对于处于正常窦性心律的麻醉、呼吸暂停且瘫痪的犬,通过胸部按压的“风箱”效应可实现出色的通气。在正常窦性心律下,10只犬完全呼吸暂停5分钟所导致的高碳酸血症和呼吸性酸血症很容易得到纠正(p<0.01)。在另外11只犬中,进行了体外胸部按压,并在心室颤动20分钟期间通过PtL持续输氧。在心脏骤停期间,pH值下降(7.38±0.01对7.19±0.02;p<0.01),但动脉血二氧化碳分压(PaCO2)(35±1对38±3mmHg)和动脉血氧分压(PaO2)(67±2对68±3mmHg)与心脏骤停前的值无显著差异。11只动物中有8只(73%)成功复苏,这与既往气管插管对照组的结果相似。使用PtL未观察到纵隔气肿并发症。我们得出结论,在心脏骤停期间,利用PtL的咽腔持续输氧并结合体外胸部按压可提供一种安全有效的氧合和通气模式。